KEGG   ENZYME: 2.8.2.11Help
Entry
EC 2.8.2.11                 Enzyme                                 

Name
galactosylceramide sulfotransferase;
GSase;
3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase;
galactocerebroside sulfotransferase;
galactolipid sulfotransferase;
glycolipid sulfotransferase;
glycosphingolipid sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate [RN:R04017 R06279]
Reaction(KEGG)
R04017 R06279(G);
(other) R05105 R06122(G) R10805
Show
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
galactosylceramide [CPD:C02686]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
galactosylceramide sulfate [CPD:C06125]
Comment
Also acts on lactosylceramide.
History
EC 2.8.2.11 created 1972, modified 1976
Pathway
Ether lipid metabolism
Sphingolipid metabolism
Metabolic pathways
Orthology
K01019  
galactosylceramide sulfotransferase
Genes
HSA: 
9514(GAL3ST1)
PTR: 
458758(GAL3ST1)
PPS: 
100977095(GAL3ST1)
GGO: 
101145588(GAL3ST1)
PON: 
100452559(GAL3ST1)
NLE: 
100607890(GAL3ST1)
MCC: 
715998(GAL3ST1)
MCF: 
102117816(GAL3ST1)
CSAB: 
103223169(GAL3ST1)
RRO: 
104668179(GAL3ST1)
CJC: 
100392008(GAL3ST1)
SBQ: 
101040941(GAL3ST1)
MMU: 
53897(Gal3st1)
RNO: 
683713(Gal3st1)
CGE: 
100756367(Gal3st1)
NGI: 
HGL: 
101706903(Gal3st1)
OCU: 
103351708(GAL3ST1)
TUP: 
102467729(GAL3ST1)
CFA: 
611960(GAL3ST1)
AML: 
100481232(GAL3ST1)
UMR: 
103681122(GAL3ST1)
FCA: 
101092797(GAL3ST1)
PTG: 
102972364(GAL3ST1)
BTA: 
513295(GAL3ST1)
BOM: 
102276313(GAL3ST1)
PHD: 
102319785(GAL3ST1)
CHX: 
102169694(GAL3ST1)
OAS: 
101112599(GAL3ST1)
SSC: 
100155265(GAL3ST1)
CFR: 
BACU: 
102998748(GAL3ST1)
LVE: 
103089977(GAL3ST1)
ECB: 
100063781(GAL3ST1)
MYB: 
102254410(GAL3ST1)
MYD: 
102768622(GAL3ST1)
PALE: 
102891895(GAL3ST1)
LAV: 
100658049(GAL3ST1)
MDO: 
100031088(GAL3ST1)
SHR: 
OAA: 
100088700(GAL3ST1)
GGA: 
417006(GAL3ST1)
MGP: 
100538663(GAL3ST1)
CJO: 
107321503(GAL3ST1)
APLA: 
101805029(GAL3ST1)
TGU: 
100218664(GAL3ST1)
GFR: 
102039149(GAL3ST1)
FAB: 
101815086(GAL3ST1)
PHI: 
102111822(GAL3ST1)
CCW: 
104694982(GAL3ST1)
FPG: 
101914565(GAL3ST1)
FCH: 
102049840(GAL3ST1)
CLV: 
102095258(GAL3ST1)
AAM: 
106494522(GAL3ST1)
ASN: 
102371784(GAL3ST1)
AMJ: 
102564060(GAL3ST1)
PSS: 
CMY: 
ACS: 
PBI: 
103053254(GAL3ST1)
GJA: 
XTR: 
100495120(gal3st1)
DRE: 
793735(gal3st1a)
TRU: 
TNG: 
MZE: 
OLA: 
XMA: 
SASA: 
LCM: 
CMK: 
103184338(gal3st1)
BFO: 
CIN: 
SPU: 
SKO: 
API: 
100572897(ACYPI55336)
ISC: 
HRO: 
LGI: 
CRG: 
OBI: 
NVE: 
ADF: 
SRE: 
 » show all
Taxonomy
Reference
1  [PMID:5850675]
  Authors
McKhann GM, Levy R, Ho W.
  Title
Metabolism of sulfatides. I. The effect of galactocerebrosides on the synthesis of sulfatides.
  Journal
Biochem. Biophys. Res. Commun. 20 (1965) 109-13.
Reference
2  [PMID:2562926]
  Authors
Sakakibara N, Gasa S, Kamio K, Makita A, Koyanagi T.
  Title
Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma.
  Journal
Cancer. Res. 49 (1989) 335-9.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9081-06-5

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