KEGG   ENZYME: 2.8.2.15Help
Entry
EC 2.8.2.15                 Enzyme                                 

Name
steroid sulfotransferase;
steroid alcohol sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate [RN:R03946]
Reaction(KEGG)
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
phenolic steroid [CPD:C02453]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
steroid O-sulfate [CPD:C02590]
Comment
Broad specificity resembling EC 2.8.2.2 alcohol sulfotransferase, but also acts on estrone.
History
EC 2.8.2.15 created 1984
Pathway
Steroid hormone biosynthesis
Reference
1  [PMID:6932974]
  Authors
Adams JB, McDonald D.
  Title
Enzymic synthesis of steroid sulphates. XIII. Isolation and properties of dehydroepiandrosterone sulphotransferase from human foetal adrenals.
  Journal
Biochim. Biophys. Acta. 615 (1980) 275-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9032-76-2

DBGET integrated database retrieval system