KEGG   ENZYME: 2.8.2.18Help
Entry
EC 2.8.2.18                 Enzyme                                 

Name
cortisol sulfotransferase;
glucocorticosteroid sulfotransferase;
glucocorticoid sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate:cortisol 21-sulfotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + cortisol = adenosine 3',5'-bisphosphate + cortisol 21-sulfate [RN:R02839]
Reaction(KEGG)
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
cortisol [CPD:C00735]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
cortisol 21-sulfate [CPD:C02822]
History
EC 2.8.2.18 created 1986
Reference
1  [PMID:6957246]
  Authors
Singer SS, Brill B.
  Title
Enzymatic sulfation of steroids. XVII. The properties of the glucocorticoid sulfotransferase activity of guinea pig liver cytosol.
  Journal
Biochim. Biophys. Acta. 712 (1982) 590-6.
Reference
2  [PMID:1278101]
  Authors
Singer SS, Giera D, Johnson J, Sylvester S.
  Title
Enzymatic sulfation of steroids: I. The enzymatic basis for the sex difference in cortisol sulfation by rat liver preparations.
  Journal
Endocrinology. 98 (1976) 963-74.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
59782-20-6

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