Entry |
|
Name |
desulfo-A47934 sulfotransferase;
StaL
|
Class |
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
 |
Sysname |
3'-phosphoadenylyl-sulfate:desulfo-A47934 sulfotransferase
|
Reaction(IUBMB) |
3'-phosphoadenylyl sulfate + desulfo-A47934 = adenosine 3',5'-bisphosphate + A47934 [RN: R10655]
|
Reaction(KEGG) |
|
Substrate |
3'-phosphoadenylyl sulfate [CPD: C00053];
desulfo-A47934 [CPD: C20759]
|
Product |
adenosine 3',5'-bisphosphate [CPD: C00054];
A47934 [CPD: C12016]
|
Comment |
The enzyme from the bacterium Streptomyces toyocaensis catalyses the final step in the biosynthesis of the glycopeptide antibiotic A47934, a naturally occuring antibiotic of the vancomycin group.
|
History |
EC 2.8.2.36 created 2014
|
Orthology |
| desulfo-A47934 sulfotransferase |
|
Reference |
|
Authors |
Lamb SS, Patel T, Koteva KP, Wright GD |
Title |
Biosynthesis of sulfated glycopeptide antibiotics by using the sulfotransferase StaL. |
Journal |
Chem. Biol. 13 (2006) 171-81. |
Sequence |
|
Reference |
|
Authors |
Shi R, Lamb SS, Bhat S, Sulea T, Wright GD, Matte A, Cygler M |
Title |
Crystal structure of StaL, a glycopeptide antibiotic sulfotransferase from Streptomyces toyocaensis. |
Journal |
J. Biol. Chem. 282 (2007) 13073-86. |
Sequence |
|
Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: |