KEGG   ENZYME: 2.8.2.9Help
Entry
EC 2.8.2.9                  Enzyme                                 

Name
tyrosine-ester sulfotransferase;
aryl sulfotransferase IV;
L-tyrosine methyl ester sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate:L-tyrosine-methyl-ester sulfotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + L-tyrosine methyl ester = adenosine 3',5'-bisphosphate + L-tyrosine methyl ester 4-sulfate [RN:R04213]
Reaction(KEGG)
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
L-tyrosine methyl ester [CPD:C03404]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
L-tyrosine methyl ester 4-sulfate [CPD:C04201]
Comment
Phenols and organic hydroxylamines can act as acceptors (cf. EC 2.8.2.1 aryl sulfotransferase).
History
EC 2.8.2.9 created 1972, deleted 1980, reinstated 1984
Reference
1  [PMID:6945304]
  Authors
Duffel MW, Jakoby WB.
  Title
On the mechanism of aryl sulfotransferase.
  Journal
J. Biol. Chem. 256 (1981) 11123-7.
Reference
2  [PMID:5441369]
  Authors
Mattock P, Jones JG.
  Title
Partial purification and properties of an enzyme from rat liver that catalyses the sulphation of L-tyrosyl derivatives.
  Journal
Biochem. J. 116 (1970) 797-803.
Reference
3  [PMID:6946725]
  Authors
Sekura RD, Jakoby WB.
  Title
Aryl sulfotransferase IV from rat liver.
  Journal
Arch. Biochem. Biophys. 211 (1981) 352-9.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9055-56-5

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