KEGG   ENZYME: 2.8.3.10Help
Entry
EC 2.8.3.10                 Enzyme                                 

Name
citrate CoA-transferase
Class
Transferases;
Transferring sulfur-containing groups;
CoA-transferases
BRITE hierarchy
Sysname
acetyl-CoA:citrate CoA-transferase
Reaction(IUBMB)
acetyl-CoA + citrate = acetate + (3S)-citryl-CoA [RN:R01323]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
citrate [CPD:C00158]
Product
acetate [CPD:C00033];
(3S)-citryl-CoA [CPD:C00566]
Comment
The enzyme is a component of EC 4.1.3.6 [citrate (pro-3S)-lyase]. Also catalyses the transfer of thioacyl carrier protein from its acetyl thioester to citrate.
History
EC 2.8.3.10 created 1984
Orthology
K01643  citrate lyase subunit alpha / citrate CoA-transferase
Genes
ECO: b0615(citF)
ECJ: JW5087(citF)
ECD: ECDH10B_0575(citF) ECDH10B_0683(citF)
EBW: BWG_0488(citF)
ECOK: ECMDS42_0476(citF)
ECE: Z0759(citF)
ECS: ECs0654
ECF: ECH74115_0703(citF)
ETW: ECSP_0669(citF)
ELX: CDCO157_0641
EOJ: ECO26_0690(citF)
EOI: ECO111_0646(citF)
EOH: ECO103_0623(citF)
ECG: E2348C_0516(citF)
EOK: G2583_0779(citF)
ECC: c0704(citF)
ECP: ECP_0646
ECI: UTI89_C0618(citF)
ECV: APECO1_1436(citF)
ECX: EcHS_A0666(citF)
ECW: EcE24377A_0637(citF)
ECM: EcSMS35_0634(citF)
ECY: ECSE_0683
ECR: ECIAI1_0599(citF)
ECQ: ECED1_0612(citF)
ECK: EC55989_0607(citF)
ECT: ECIAI39_0591(citF)
EOC: CE10_0614(citF)
EUM: ECUMN_0708(citF)
ECZ: ECS88_0656(citF)
ELO: EC042_0652(citF)
ELH: ETEC_0644
ESE: ECSF_0555
ESO: O3O_06780
ESM: O3M_18495
ESL: O3K_18515
EBR: ECB_00583(citF)
EBD: ECBD_3037
EKF: KO11_20590(citF)
EAB: ECABU_c06660(citF)
EDJ: ECDH1ME8569_0585(citF)
EIH: ECOK1_0626(citF)
ENA: ECNA114_0557(citF)
EUN: UMNK88_651(citF)
ELW: ECW_m0670(citF)
ELL: WFL_03330(citF)
ELC: i14_0675(citF)
ELD: i02_0675(citF)
ELP: P12B_c0599(citF)
EBL: ECD_00583(citF)
EBE: B21_00572(citF)
ELF: LF82_0310(citF)
ECOI: ECOPMV1_00634(citF)
ECOJ: P423_03020
ECOO: ECRM13514_0639(citF)
ECOH: ECRM13516_0584(citF)
ECOS: EC958_0734(citF)
EFE: EFER_0035(citF)
EAL: EAKF1_ch0846(citF)
EMA: C1192_09635(citF)
STY: STY0070(citF2) STY0670(citF)
STT: t0063(citF) t2246(citF)
STM: STM0061(citF2) STM0621(citF)
SEO: STM14_0072(citF2) STM14_0722(citF)
SEY: SL1344_0062(citF2) SL1344_0609(citF)
SEJ: STMUK_0062(citF2) STMUK_0626(citF)
SEB: STM474_0064(citF2) STM474_0642(citF)
SEF: UMN798_0069(citF2) UMN798_0671(citF)
SENR: STMDT2_00621(citF2) STMDT2_06121(citF)
SEND: DT104_00611(citF2) DT104_06501(citF)
SPT: SPA0062(citF) SPA2113(citF)
SEI: SPC_0065(citF2) SPC_0634(citF)
SEC: SCH_0055(citF2) SCH_0650(citF)
SEH: SeHA_C0065(citF) SeHA_C0734(citF)
SEE: SNSL254_A0066(citF) SNSL254_A0675(citF)
SEW: SeSA_A0067(citF) SeSA_A0780(citF)
SEA: SeAg_B0068(citF) SeAg_B0661(citF)
SED: SeD_A0066(citF) SeD_A0721(citF)
SEG: SG0065(citF2) SG0625(citF)
SEL: SPUL_0065(citF2) SPUL_2343(citF)
SEGA: SPUCDC_0065(citF2) SPUCDC_2329(citF)
SET: SEN0062(citF2) SEN0590(citF)
SEEP: I137_00290
SENB: BN855_6140(citF) BN855_620(citF2)
SBG: SBG_0529(citF)
SBZ: A464_595
SFL: SF0532(citF)
SFX: S0539(citF)
SFV: SFV_0568(citF)
SFE: SFxv_0588(citF)
SFN: SFy_0700
SFS: SFyv_0742
SFT: NCTC1_00560(citF)
SSN: SSON_0567(citF)
SBO: SBO_0480(citF)
SBC: SbBS512_E0529(citF)
ENC: ECL_04295
ECLO: ENC_32170
EEC: EcWSU1_03766(citF)
ECLX: LI66_18840
ECLY: LI62_20300
CSK: ES15_0600(citF)
CTU: CTU_35630(citF)
KPN: KPN_00037(citF2)
KPT: VK055_2538(citF)
KPE: KPK_4712(citF)
KPJ: N559_4395
KPNU: LI86_22585
KPNK: BN49_4303(citF) BN49_4527
KVA: Kvar_4352
EAR: CCG31796
KQV: B8P98_02640(citF) B8P98_23610(citF)
CKO: CKO_02544
CRO: ROD_06301(citF)
CWE: CO701_15695(citF)
CAMA: F384_02725
CAF: AL524_19565(citF)
CIF: AL515_07735(citF)
CFAR: CI104_07435(citF) CI104_19395(citF)
CIR: C2U53_16640(citF)
EBT: EBL_c06540(citF)
LNI: CWR52_00505(citF) CWR52_16395(citF)
EBF: D782_0734
YEN: YE2650(citF)
YEY: Y11_15341
YEL: LC20_02072(citF)
YEW: CH47_1994(citF)
YET: CH48_3231(citF)
YEE: YE5303_24151(citF)
YAL: AT01_25(citF)
YFR: AW19_802(citF)
YIN: CH53_3449(citF)
YKR: CH54_860(citF)
YRO: CH64_168(citF)
YRU: BD65_739(citF)
YMA: DA391_08455(citF)
SPE: Spro_3168
SRL: SOD_c30530(citF)
SMAF: D781_2920
SMW: SMWW4_v1c32160(citF)
SMAR: SM39_2659(citF)
SMAC: SMDB11_2457(citF)
SERF: L085_12500
SERA: Ser39006_011310(citF) Ser39006_015635(citF)
RAA: Q7S_07730
ECA: ECA2571(citF)
PATR: EV46_12420
PATO: GZ59_19920(citF)
PCT: PC1_1755
PEC: W5S_1974
DDD: Dda3937_00476(citF_1) Dda3937_04528(citF_2)
DDQ: DDI_1742
DFN: CVE23_10185(citF)
PSI: S70_18550
PSX: DR96_2644(citF)
PRG: RB151_015710(citF)
PALA: CO695_16390(citF)
ETR: ETAE_0224(citF)
ETD: ETAF_0194
ETE: ETEE_1982(citF)
HIN: HI0022(citF)
HIT: NTHI0029(citF)
HIU: HIB_00220
HIE: R2846_0625(citF)
HIZ: R2866_0683(citF)
HIK: HifGL_001520(citF)
HIA: H733_0714(citF)
HIW: NTHI477_01050(citF)
HIC: NTHIC486_01021(citF)
HIX: NTHI723_01695(citF)
HDU: HD_1243(citF)
ASU: Asuc_1196
AAT: D11S_0858
AAN: D7S_01552
AACN: AANUM_0935(citF)
BTO: WQG_12880
BTRE: F542_9160
BTRH: F543_10500
BTRA: F544_13220
VCH: VC0799
VCE: Vch1786_I0305(citF)
VCO: VC0395_A0326(citF)
VCR: VC395_0816(citF)
VCM: VCM66_0757(citF)
VCI: O3Y_03720
VCS: MS6_0609
VCX: VAA049_2900(citF)
VCZ: VAB027_1451(citF)
VHR: AL538_01515(citF)
VAN: VAA_02027
VAU: VANGNB10_cI1191(citF)
VMI: AL543_13275(citF)
PPR: PBPRA2292(CITF)
CNC: CNE_BB1p09780(citF)
RFR: Rfer_2407
RGE: RGE_23160(citF)
SMUL: SMUL_2346(citF)
SHAL: SHALO_2092
SULJ: SJPD1_2119
GBM: Gbem_3858(citF)
GEM: GM21_3943
GEB: GM18_4289
PPD: Ppro_1084
RPE: RPE_3430
MPO: Mpop_1249
DSH: Dshi_1427(citF)
SPSE: SULPSESMR1_03025(citF)
AHT: ANTHELSMS3_00919(citF)
ASZ: ASN_2632(citF)
AZL: AZL_a08480(citF)
PPY: PPE_03597
LLA: L0041(citF)
LPK: LACPI_1079(citF)
SPY: SPy_1189(citF)
SPZ: M5005_Spy0907(citF)
SPYM: M1GAS476_0963(citF)
SPM: spyM18_1140(citF)
SPG: SpyM3_0834(citF)
SPS: SPs1034
SPH: MGAS10270_Spy1021(citF)
SPI: MGAS10750_Spy1057(citF)
SPF: SpyM50890(citF)
SPB: M28_Spy0880(citF)
STG: MGAS15252_0905(citF)
SOZ: Spy49_0937(citF)
STZ: SPYALAB49_000898(citF)
STX: MGAS1882_0900(citF)
SPYA: A20_0944(citF)
SPYH: L897_04490
SMU: SMU_1021(cilA)
SMC: SmuNN2025_1002(cilA)
SMJ: SMULJ23_1011(cilA)
SMUA: SMUFR_0890(citF)
SEZ: Sez_0996(citF)
SEQ: SZO_09740
SEZO: SeseC_01297(citF)
SEQU: Q426_04220
SEU: SEQ_1199
SUB: SUB1586(citF)
SDS: SDEG_0985(citF)
SDC: SDSE_1014(citF)
STK: STP_0116(citF)
SIK: K710_0376
LPL: lp_1109(citF)
LPJ: JDM1_0915(citF)
LPT: zj316_1140(citF)
LPS: LPST_C0889(citF)
LPZ: Lp16_0892
LAC: LBA0917(citF)
LAD: LA14_0938
LAF: SD55_0938(citF)
LSA: LCA_1224(citF)
LCA: LSEI_1857
LPAP: LBPC_1816
LCB: LCABL_20810(citF)
LCS: LCBD_2050
LCE: LC2W_2032
LCW: BN194_20310(citF)
LRU: HMPREF0538_20648(citF)
LRT: LRI_0443
LHE: lhv_0990
LHL: LBHH_1196
LHV: lhe_0920
LHH: LBH_0816
LHD: HUO_07155
LFF: LBFF_1032(citF-1) LBFF_1033 LBFF_1725(citF-2)
LRH: LGG_01914(citF)
LRG: LRHM_1837
LRL: LC705_01902(citF)
LRA: LRHK_1900(citF)
LCR: LCRIS_00971(citF)
LKE: WANG_0745(citF)
LSN: LSA_12980(citF)
LAE: LBAT_0824
PCE: PECL_256(citF)
EFA: EF3319(citF)
EFL: EF62_0378(citF)
EFI: OG1RF_12564(citF)
EFS: EFS1_2719(citF)
EFN: DENG_03211(citF)
EFQ: DR75_2036(citF)
ENE: ENT_00410
EFAU: EFAU085_p1077(citF)
EFM: M7W_157
ECAS: ECBG_03039
EMU: EMQU_1783(citF)
EGA: AL523_04195(citF)
MPS: MPTP_1973
MPX: MPD5_1773
THL: TEH_07990(citF)
OOE: OEOE_0423
LCI: LCK_00110(cilA)
LKI: LKI_04115
LGS: LEGAS_0216(citF)
CPE: CPE1149
CPR: CPR_1165(citF)
CSR: Cspa_c37390(citF1) Cspa_c44180(citF2)
CSQ: CSCA_4333
CACE: CACET_c34360(citF)
FPR: FP2_25370
BHAN: CGC63_11315(citF)
CSO: CLS_26900
EAC: EAL2_808p05940(citF)
PBQ: C3V37_01000(citF)
DSY: DSY3038
DHD: Dhaf_4206
SGY: Sgly_3229
BPRM: CL3_32150
TAE: TepiRe1_2443(citF)
PED: ING2D1G_1036(citF)
VPR: Vpar_1399
VRM: 44547418_01485(citF)
AIN: Acin_0571(citF)
ERH: ERH_0753(citF)
MLAC: CP520_03355(citF)
EML: EMELA_v1c00420(citF)
SCQ: SCULI_v1c01700(citF)
SERI: SERIO_v1c06500(citF)
SHJ: SHELI_v1c10400(citF)
SCOU: SCORR_v1c05670(citF)
MBJ: KQ51_00882(citF)
TDE: TDE1631(citF)
TPI: TREPR_1288(citF_2) TREPR_3316(citF_1)
TPED: TPE_1047 TPE_2191(citF)
BHY: BHWA1_02092(citF)
FNU: FN1380
FPD: CTM68_03585(citF)
SBR: SY1_17650
BLQ: L21SP5_01301(citF_1) L21SP5_03885(citF_2)
IAL: IALB_1146(citF)
MRO: MROS_2217
CABY: Cabys_2629
ABI: Aboo_0970
 » show all
Taxonomy
Reference
1  [PMID:336371]
  Authors
Dimroth P, Loyal R, Eggerer H.
  Title
Characterization of the isolated transferase subunit of citrate lyase as a CoA-Transferase. Evidence against a covalent enzyme-substrate intermediate.
  Journal
Eur. J. Biochem. 80 (1977) 479-88.
Other DBs
ExplorEnz - The Enzyme Database: 2.8.3.10
IUBMB Enzyme Nomenclature: 2.8.3.10
ExPASy - ENZYME nomenclature database: 2.8.3.10
BRENDA, the Enzyme Database: 2.8.3.10
CAS: 65187-14-6

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