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Entry
EC 2.8.3.12                 Enzyme                                 

Name
glutaconate CoA-transferase
Class
Transferases;
Transferring sulfur-containing groups;
CoA-transferases
BRITE hierarchy
Sysname
acetyl-CoA:(E)-glutaconate CoA-transferase
Reaction(IUBMB)
acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA [RN:R03884]
Reaction(KEGG)
R03884;
(other) R04000 R05509
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Substrate
acetyl-CoA [CPD:C00024];
(E)-glutaconate [CPD:C02214]
Product
acetate [CPD:C00033];
glutaconyl-1-CoA [CPD:C02411]
Comment
Glutarate, (R)-2-hydroxyglutarate, propenoate and propanoate, but not (Z)-glutaconate, can also act as acceptors.
History
EC 2.8.3.12 created 1984, modified 2002
Pathway
ec00643  Styrene degradation
ec00650  Butanoate metabolism
ec01120  Microbial metabolism in diverse environments
Orthology
K01039  glutaconate CoA-transferase, subunit A
K01040  glutaconate CoA-transferase, subunit B
Genes
SOD: Sant_2230 Sant_2231 Sant_2232 Sant_2233
PLU: plu0143 plu0144
XCC: XCC0364(gctA) XCC0365(gctB)
XCB: XC_0376 XC_0377
XCA: xcc-b100_0390(gctA) xcc-b100_0391(gctB)
XCP: XCR_4150 XCR_4151
XCV: XCV0378(gctA) XCV0379(gctB)
XAX: XACM_0352(gctA) XACM_0353(gctB)
XAC: XAC0364(gctA) XAC0365(gctB)
XCI: XCAW_00771(gctA) XCAW_00772(gctB)
XOP: PXO_02904
XPH: XppCFBP6546_10000(XppCFBP6546P_10000)
LCP: LC55x_1053(catI) LC55x_1054(catJ)
PAEV: N297_232(catI) N297_233(catJ)
PAEI: N296_232(catI) N296_233(catJ)
PAU: PA14_02760(catI) PA14_02770(pcaJ)
PNC: NCGM2_0232(catI) NCGM2_0233(pcaJ)
PAEB: NCGM1900_0217(catI) NCGM1900_0218(pcaJ)
PAEC: M802_231(catI) M802_232(catJ)
PAEO: M801_232(catI) M801_233(catJ)
PCQ: PcP3B5_32740(catJ) PcP3B5_32750(catI)
PST: PSPTO_4308(catJ) PSPTO_4309(catI)
PSP: PSPPH_4018(catJ) PSPPH_4019(catI)
PFL: PFL_1317(catI) PFL_1318(catJ)
PPRC: PFLCHA0_c13530(catI) PFLCHA0_c13540(catJ)
PPRO: PPC_1371(catI) PPC_1372(catJ)
PFS: PFLU_1363 PFLU_1364(gctB)
PFC: PflA506_1320(catI) PflA506_1321(catJ)
PEN: PSEEN1163(catI) PSEEN1164(catJ)
PSA: PST_1254(pcaI) PST_1255(pcaJ)
PSZ: PSTAB_1162(catI) PSTAB_1163(pcaJ)
PSR: PSTAA_1218(pcaI) PSTAA_1219(pcaJ)
PSES: PSCI_2948(catI) PSCI_2949
PSEC: CCOS191_4274(catJ) CCOS191_4275(catI)
PSOS: POS17_1338(catI) POS17_1339(catJ)
AVN: Avin_38210(pcaJ) Avin_38220(pcaI)
AVL: AvCA_38210(pcaJ) AvCA_38220(pcaI)
AVD: AvCA6_38210(pcaJ) AvCA6_38220(pcaI)
ACX: Achr_12030(pcaI) Achr_12040(pcaJ)
PTN: PTRA_a1033(gctA) PTRA_a1034(gctB)
PNG: PNIG_a1085(gctA) PNIG_a1086(gctB)
MHC: MARHY0271(catJ) MARHY0272(catI)
HEL: HELO_3961(gctB) HELO_3962(catI)
HBE: BEI_0587(gctB) BEI_0588(gctA)
REH: H16_B0655(h16_B0655) H16_B0656(h16_B0656)
CTI: RALTA_B0497(gctA) RALTA_B0498(gctB)
BPT: Bpet3678(gctA) Bpet3679(gctB)
BHZ: ACR54_04600(catJ) ACR54_04601(catI)
DML: Dmul_22880(gctB) Dmul_22890(gctA) Dmul_24380(catI) Dmul_24390(catJ)
DAT: HRM2_38680(gctB) HRM2_38690(gctA)
DTO: TOL2_C01230(gctB) TOL2_C01240(gctA) TOL2_C15540(gctA2) TOL2_C15550(gctB2) TOL2_C17550(gctA3) TOL2_C17560(atoD)
SMX: SM11_pD0124(pcaJ) SM11_pD0125(pcaI)
SMEL: SM2011_b20587(pcaI) SM2011_b20588(pcaJ)
SFD: USDA257_c16070(catI) USDA257_c16080(catJ)
BJA: bll1292 bll1293(gctA)
VGO: GJW-30_1_03980(catI) GJW-30_1_03981(catJ)
HDI: HDIA_0299(catI) HDIA_0300(catJ)
PSF: PSE_2281(pcaI) PSE_2282(pcaJ)
SPHB: EP837_03388(gctB) EP837_03389(gctA)
ALI: AZOLI_p40024(catI) AZOLI_p40025(catJ)
BKW: BkAM31D_02935(catI) BkAM31D_02950(catJ_2)
ASOC: CB4_03428(catJ) CB4_03429(gctA)
CACE: CACET_c03500(gctA) CACET_c03510(catJ)
CSO: CLS_16260
SWO: Swol_1481
PTH: PTH_2043(AtoD) PTH_2044(AtoD)
OVA: OBV_10820(gctB) OBV_10830(gctA)
SAY: TPY_1604(gctB) TPY_1605
BPRS: CK3_23930
PED: ING2D1G_1423(gctB) ING2D1G_1424(gctA)
AIN: Acin_0316(gctA) Acin_0317(gctB)
ASD: AS9A_0957
NFR: ERS450000_00530(catI) ERS450000_00531(catJ_1)
RER: RER_20830(catJ) RER_20840(catI)
REQ: REQ_00850
SMA: SAVERM_6202(cotA)
SCT: SCAT_5625
SVE: SVEN_1658
SALU: DC74_7434
SALL: SAZ_38375
STRE: GZL_01198
STRM: M444_10245
SAMB: SAM23877_6562(catJ) SAM23877_6563(catI)
SRW: TUE45_02542(gctA)
SLAU: SLA_1556
SALJ: SMD11_0775
SLX: SLAV_27320(gctA)
NCA: Noca_4813
NDK: I601_0611(catI)
PSIM: KR76_25105
TCU: Tcur_4619
SEN: SACE_3515(catJ) SACE_3516(catI) SACE_4007 SACE_4008(catI) SACE_4876(gctB) SACE_4877(gctA)
AMD: AMED_1857(gctA) AMED_1858(gctB)
AMM: AMES_1843(gctA) AMES_1844(gctB)
AMZ: B737_1844(gctA) B737_1845(gctB)
AOI: AORI_6022(gctB) AORI_6023(gctA)
AJA: AJAP_09320(catI) AJAP_09325(catJ)
AMQ: AMETH_4259(catI) AMETH_4260(gctB) AMETH_5397(gctB) AMETH_5398(gctA)
SESP: BN6_27590(catJ) BN6_27600(catI)
ALL: CRK57767
SAQ: Sare_2804
ATM: ANT_02010(catJ) ANT_02020(catI)
ABAT: CFX1CAM_0254(catJ) CFX1CAM_0255(catI)
GES: VT84_03265(gctA) VT84_37255(catJ)
ABAC: LuPra_04014(catJ) LuPra_04015(catI)
TTK: TST_1023(gctA) TST_1024(gctB)
MOX: DAMO_0596 DAMO_0597(AtoA)
AFU: AF_1199
SSO: SSO1083(gctA) SSO1085(gctB)
LOKI: Lokiarch_06790(catI_1) Lokiarch_06800(catJ_1) Lokiarch_12250(catI_2) Lokiarch_12260(catJ_2) Lokiarch_23320(catJ_3) Lokiarch_23330(gctA) Lokiarch_29040(catI_3)
 » show all
Taxonomy
Reference
1  [PMID:6945182]
  Authors
Buckel W, Dorn U, Semmler R.
  Title
Glutaconate CoA-transferase from Acidaminococcus fermentans.
  Journal
Eur. J. Biochem. 118 (1981) 315-21.
Other DBs
ExplorEnz - The Enzyme Database: 2.8.3.12
IUBMB Enzyme Nomenclature: 2.8.3.12
ExPASy - ENZYME nomenclature database: 2.8.3.12
UM-BBD (Biocatalysis/Biodegradation Database): 2.8.3.12
BRENDA, the Enzyme Database: 2.8.3.12
CAS: 79078-99-2

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