KEGG   ENZYME: 2.8.3.13Help
Entry
EC 2.8.3.13                 Enzyme                                 

Name
succinate---hydroxymethylglutarate CoA-transferase;
hydroxymethylglutarate coenzyme A-transferase;
dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase
Class
Transferases;
Transferring sulfur-containing groups;
CoA-transferases
BRITE hierarchy
Sysname
succinyl-CoA:3-hydroxy-3-methylglutarate CoA-transferase
Reaction(IUBMB)
succinyl-CoA + 3-hydroxy-3-methylglutarate = succinate + (S)-3-hydroxy-3-methylglutaryl-CoA [RN:R02084]
Reaction(KEGG)
Substrate
succinyl-CoA [CPD:C00091];
3-hydroxy-3-methylglutarate [CPD:C03761]
Product
succinate [CPD:C00042];
(S)-3-hydroxy-3-methylglutaryl-CoA [CPD:C00356]
Comment
Malonyl-CoA can also act as donor, but more slowly.
History
EC 2.8.3.13 created 1984
Orthology
K18703  
succinate---hydroxymethylglutarate CoA-transferase
Genes
HSA: 
79783(SUGCT)
PTR: 
463372(SUGCT)
PPS: 
100986046(SUGCT)
GGO: 
101151689(C7H7orf10)
PON: 
100439966(SUGCT)
NLE: 
100604796(SUGCT)
MCC: 
702855(SUGCT)
MCF: 
102117690(SUGCT)
CSAB: 
103226178(SUGCT)
RRO: 
104663124(SUGCT)
CJC: 
100399458(SUGCT)
SBQ: 
101045888(SUGCT)
MMU: 
192136(Sugct)
RNO: 
361253(Sugct)
CGE: 
100770206(Sugct)
NGI: 
103736749(Sugct)
HGL: 
101704628(Sugct)
OCU: 
100344733(SUGCT)
TUP: 
102500635(SUGCT)
CFA: 
483247(SUGCT)
AML: 
100466463(SUGCT)
UMR: 
103674695(SUGCT)
FCA: 
101090248(SUGCT)
PTG: 
102969712(SUGCT)
BTA: 
100125578(SUGCT)
BOM: 
102277643(SUGCT)
PHD: 
102331925(SUGCT)
CHX: 
102189185(SUGCT)
OAS: 
101121005(SUGCT)
SSC: 
106506875(SUGCT)
CFR: 
102518036(SUGCT)
BACU: 
103011770(SUGCT)
LVE: 
103073879(SUGCT)
ECB: 
100063665(SUGCT)
MYB: 
102255717(SUGCT)
MYD: 
102755997(SUGCT)
LAV: 
100662735(SUGCT)
MDO: 
100017716(SUGCT)
SHR: 
OAA: 
100076800(SUGCT)
GGA: 
420768(C7ORF10)
MGP: 
100541558(SUGCT)
CJO: 
107309842(SUGCT)
APLA: 
101795646(SUGCT)
TGU: 
100220077(SUGCT)
GFR: 
102042813(SUGCT)
FAB: 
101815381(SUGCT)
PHI: 
102102839(SUGCT)
CCW: 
104688907(SUGCT)
FPG: 
101914214(SUGCT)
FCH: 
102058344(SUGCT)
CLV: 
102092162(SUGCT)
AAM: 
106495271(SUGCT)
ASN: 
102380883(SUGCT)
AMJ: 
102565653(SUGCT)
PSS: 
102457624(SUGCT)
CMY: 
102938246(SUGCT)
ACS: 
100560657(sugct)
PBI: 
103051719(SUGCT)
GJA: 
107125736(SUGCT)
XLA: 
734617(sugct.L)
XTR: 
100490876(sugct)
DRE: 
TRU: 
101079570(sugct)
TNG: 
MZE: 
101479221(sugct)
OLA: 
101160363(sugct)
XMA: 
102217127(sugct)
SASA: 
LCM: 
CMK: 
103181542(sugct)
BFO: 
CIN: 
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD20057(Dsim_GD20057)
DWI: 
DYA: 
Dyak_GE25064(dyak_GLEANR_8703) Dyak_GE28146
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
BIM: 
BTER: 
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
TCA: 
BMOR: 
DPL: 
PXY: 
API: 
PHU: 
DPX: 
ISC: 
HRO: 
LGI: 
CRG: 
OBI: 
NVE: 
ADF: 
HMG: 
TAD: 
GSL: 
YLI: 
NCR: 
NTE: 
NEUTE1DRAFT61271(NEUTE1DRAFT_61271)
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
FPU: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
VDA: 
ELA: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_738164(AO090001000425)
ANG: 
ANI_1_676164(An18g05120)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
PBN: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
CNE: 
CNB: 
CGI: 
TMS: 
DSQ: 
PCO: 
SHS: 
HIR: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT113921(AGABI1DRAFT_113921)
ABV: 
AGABI2DRAFT193757(AGABI2DRAFT_193757)
CPUT: 
SLA: 
WSE: 
WIC: 
UMA: 
PFP: 
PGR: 
MLR: 
SRE: 
TET: 
PTM: 
OCG: 
OCO: 
 » show all
Taxonomy
Reference
1  [PMID:6946836]
  Authors
Deana R, Rigoni F, Deana AD, Galzigna L.
  Title
Submitochondrial localization and partial purification of the succinylCoA: 3-hydroxy-3-methylglutarate coenzyme A transferase from rat liver.
  Journal
Biochim. Biophys. Acta. 662 (1981) 119-24.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
80237-90-7

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