KEGG   ENZYME: 2.8.3.14Help
Entry
EC 2.8.3.14                 Enzyme                                 

Name
5-hydroxypentanoate CoA-transferase;
5-hydroxyvalerate CoA-transferase;
5-hydroxyvalerate coenzyme A transferase
Class
Transferases;
Transferring sulfur-containing groups;
CoA-transferases
BRITE hierarchy
Sysname
acetyl-CoA:5-hydroxypentanoate CoA-transferase
Reaction(IUBMB)
acetyl-CoA + 5-hydroxypentanoate = acetate + 5-hydroxypentanoyl-CoA [RN:R04057]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
5-hydroxypentanoate [CPD:C02804]
Product
acetate [CPD:C00033];
5-hydroxypentanoyl-CoA [CPD:C03237]
Comment
Propanoyl-CoA, acetyl-CoA, butanoyl-CoA and some other acyl-CoAs can act as substrates, but more slowly than 5-hydroxypentanoyl-CoA.
History
EC 2.8.3.14 created 1992
Reference
1  [PMID:2085413]
  Authors
Eikmanns U, Buckel W.
  Title
Properties of 5-hydroxyvalerate CoA-transferase from Clostridium aminovalericum.
  Journal
Biol. Chem. Hoppe. Seyler. 371 (1990) 1077-82.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
111684-68-5

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