KEGG   ENZYME: 2.8.3.17Help
Entry
EC 2.8.3.17                 Enzyme                                 

Name
cinnamoyl-CoA:phenyllactate CoA-transferase;
FldA
Class
Transferases;
Transferring sulfur-containing groups;
CoA-transferases
BRITE hierarchy
Sysname
(E)-cinnamoyl-CoA:(R)-phenyllactate CoA-transferase
Reaction(IUBMB)
(E)-cinnamoyl-CoA + (R)-phenyllactate = (E)-cinnamate + (R)-phenyllactyl-CoA [RN:R07796]
Reaction(KEGG)
Substrate
(E)-cinnamoyl-CoA [CPD:C16256];
(R)-phenyllactate [CPD:C05607]
Product
(E)-cinnamate [CPD:C00423];
(R)-phenyllactyl-CoA [CPD:C16257]
Comment
3-Phenylproprionate is a better CoA acceptor than (R)-phenyllactate in vitro. The enzyme from Clostridium sporogenes is specific for derivatives of 3-phenylpropionate and 4-phenylbutyrate.
History
EC 2.8.3.17 created 2003
Pathway
Tropane, piperidine and pyridine alkaloid biosynthesis
Orthology
K13607  
cinnamoyl-CoA:phenyllactate CoA-transferase
Genes
CBO: 
CBO3292(fldA)
CBA: 
CLB_3348(fldA)
CBH: 
CLC_3234(fldA)
CBY: 
CLM_3725(fldA)
CBL: 
CLK_2708(fldA)
CBB: 
CLD_1231(fldA)
CBI: 
CLJ_B3572(fldA)
CBF: 
CLI_3462(fldA)
CBM: 
CBF_3444(fldA)
CBJ: 
CLD: 
CLO: 
 » show all
Taxonomy
Reference
1  [PMID:10849007]
  Authors
Dickert S, Pierik AJ, Linder D, Buckel W.
  Title
The involvement of coenzyme A esters in the dehydration of (R)-phenyllactate to (E)-cinnamate by Clostridium sporogenes.
  Journal
Eur. J. Biochem. 267 (2000) 3874-84.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
289682-21-9

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