KEGG   ENZYME: 2.8.3.9Help
Entry
EC 2.8.3.9                  Enzyme                                 
Name
butyrate---acetoacetate CoA-transferase;
butyryl coenzyme A-acetoacetate coenzyme A-transferase;
butyryl-CoA-acetoacetate CoA-transferase
Class
Transferases;
Transferring sulfur-containing groups;
CoA-transferases
BRITE hierarchy
Sysname
butanoyl-CoA:acetoacetate CoA-transferase
Reaction(IUBMB)
butanoyl-CoA + acetoacetate = butanoate + acetoacetyl-CoA [RN:R01365]
Reaction(KEGG)
Substrate
butanoyl-CoA [CPD:C00136];
acetoacetate [CPD:C00164]
Product
butanoate [CPD:C00246];
acetoacetyl-CoA [CPD:C00332]
Comment
Butanoate, acetoacetate and their CoA thioesters are the preferred substrates, but the enzyme also acts, more slowly, on the derivatives of a number of C2 to C6 monocarboxylic acids.
Orthology
K01036  
butyrate-acetoacetate CoA-transferase
Genes
RPC: 
OIH: 
CAC: 
CA_P0163(ctfa) CA_P0164(ctfb)
FNU: 
Taxonomy
Reference
1  [PMID:624727]
  Authors
Barker HA, Jeng IM, Neff N, Robertson JM, Tam FK, Hosaka S.
  Title
Butyryl-CoA:acetoacetate CoA-transferase from a lysine-fermenting Clostridium.
  Journal
J. Biol. Chem. 253 (1978) 1219-25.
  Organism
Clostridiurn sticklandii, Ctostridium sp.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
66231-37-6
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