KEGG   ENZYME: 3.1.1.10Help
Entry
EC 3.1.1.10                 Enzyme                                 

Name
tropinesterase;
tropine esterase;
atropinase;
atropine esterase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
atropine acylhydrolase
Reaction(IUBMB)
atropine + H2O = tropine + tropate [RN:R03563]
Reaction(KEGG)
Substrate
atropine [CPD:C01479];
H2O [CPD:C00001]
Product
tropine [CPD:C00729];
tropate [CPD:C01456]
Comment
Also acts on cocaine and other tropine esters.
History
EC 3.1.1.10 created 1961, deleted 1972, reinstated 1976
Pathway
Tropane, piperidine and pyridine alkaloid biosynthesis
Biosynthesis of secondary metabolites
Reference
1
  Authors
Glick, D., Glaubach, S. and Moore, D.H.
  Title
Azolesterase activities of electrophoretically separated proteins of serum.
  Journal
J. Biol. Chem. 144 (1942) 525-528.
Reference
2  [PMID:4435736]
  Authors
Moog P, Krisch K.
  Title
[The purification and characterization of atropine esterase from rabbit liver microsomes (author's transl)]
  Journal
Hoppe. Seylers. Z. Physiol. Chem. 355 (1974) 529-42.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
59536-71-9

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