KEGG   ENZYME: 3.1.1.39Help
Entry
EC 3.1.1.39                 Enzyme                                 

Name
actinomycin lactonase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
actinomycin lactonohydrolase
Reaction(IUBMB)
actinomycin + H2O = actinomycinic monolactone [RN:R03711]
Reaction(KEGG)
Substrate
actinomycin [CPD:C01775];
H2O [CPD:C00001]
Product
actinomycinic monolactone [CPD:C03597]
History
EC 3.1.1.39 created 1972
Reference
1  [PMID:4191854]
  Authors
Hou CT, Perlman D.
  Title
Microbial transformations of peptide antibiotics. V. Purification and properties of the actinomycin lactonase from Actinoplanes missouriensis.
  Journal
J. Biol. Chem. 245 (1970) 1289-95.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37288-09-8

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