KEGG   ENZYME: 3.1.1.56Help
Entry
EC 3.1.1.56                 Enzyme                                 

Name
methylumbelliferyl-acetate deacetylase;
esterase D
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
4-methylumbelliferyl-acetate acylhydrolase
Reaction(IUBMB)
4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate [RN:R04141]
Reaction(KEGG)
Substrate
4-methylumbelliferyl acetate [CPD:C03837];
H2O [CPD:C00001]
Product
4-methylumbelliferone [CPD:C03081];
acetate [CPD:C00033]
Comment
Acts on short-chain acyl esters of 4-methylumbelliferone, but not on naphthyl, indoxyl or thiocholine esters.
History
EC 3.1.1.56 created 1986
Orthology
K03927  
carboxylesterase 2
Genes
HSA: 
8824(CES2)
PTR: 
740768(CES2)
PPS: 
100994078(CES2)
GGO: 
PON: 
100431215(CES2)
MCF: 
MMU: 
102022(Ces2a) 234669(Ces2b) 234671(Ces2c) 234673(Ces2e) 436059(Ces2h) 72361(Ces2g)
RNO: 
100365112(Ces2) 100910144(Ces2) 171118(Ces2c) 246252(Ces2a) 291952(Ces2g) 498940(Ces2h) 679149 679368
CGE: 
HGL: 
TUP: 
102475270(CES2)
CFA: 
489769(CES2)
AML: 
100482589(CES2)
FCA: 
101096775(CES2)
PTG: 
102953134(CES2)
BTA: 
505928(CES2)
BOM: 
102275039(CES2)
PHD: 
102328178(CES2)
CHX: 
102175705(CES2)
SSC: 
100626781(CES2)
CFR: 
102510209(CES2)
ECB: 
100065668(CES2)
MDO: 
100144614(CES2.1) 100144616(CES2.3) 100144617(CES2.2)
SHR: 
GGA: 
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
PSS: 
ACS: 
XTR: 
DRE: 
561967(wu:fb62a02) 566132(ces2)
MZE: 
XMA: 
BFO: 
CIN: 
DPO: 
CEL: 
CELE_F13H6.3(F13H6.3) CELE_F13H6.4(F13H6.4)
CBR: 
FGR: 
NHE: 
SSL: 
BFU: 
ANI: 
AFM: 
AOR: 
AOR_1_970144(AO090023000559)
ANG: 
ANI_1_216174(An10g00780) ANI_1_712104(An12g05590)
AFV: 
NFI: 
PCS: 
 » show all
Taxonomy
Reference
1  [PMID:4768551]
  Authors
Hopkinson DA, Mestriner MA, Cortner J, Harris H.
  Title
Esterase D: a new human polymorphism.
  Journal
Ann. Hum. Genet. 37 (1973) 119-37.
  Organism
Homo sapiens
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
83380-83-0

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