KEGG   ENZYME: 3.1.1.63Help
Entry
EC 3.1.1.63                 Enzyme                                 

Name
11-cis-retinyl-palmitate hydrolase;
11-cis-retinol palmitate esterase;
RPH
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
11-cis-retinyl-palmitate acylhydrolase
Reaction(IUBMB)
11-cis-retinyl palmitate + H2O = 11-cis-retinol + palmitate [RN:R03049]
Reaction(KEGG)
Substrate
11-cis-retinyl palmitate [CPD:C03455];
H2O [CPD:C00001]
Product
11-cis-retinol [CPD:C00899];
palmitate [CPD:C00249]
Comment
Activated by bile salts.
History
EC 3.1.1.63 created 1989
Pathway
Retinol metabolism
Reference
1  [PMID:3793734]
  Authors
Blaner WS, Das SR, Gouras P, Flood MT.
  Title
Hydrolysis of 11-cis- and all-trans-retinyl palmitate by homogenates of human retinal epithelial cells.
  Journal
J. Biol. Chem. 262 (1987) 53-8.
Reference
2  [PMID:6743673]
  Authors
Blaner WS, Prystowsky JH, Smith JE, Goodman DS.
  Title
Rat liver retinyl palmitate hydrolase activity. Relationship to cholesteryl oleate and triolein hydrolase activities.
  Journal
Biochim. Biophys. Acta. 794 (1984) 419-27.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
106389-23-5

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