KEGG   ENZYME: 3.1.1.74Help
Entry
EC 3.1.1.74                 Enzyme                                 

Name
cutinase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
cutin hydrolase
Reaction(IUBMB)
cutin + H2O = cutin monomers [RN:R05793]
Reaction(KEGG)
Substrate
cutin [CPD:C07299];
H2O [CPD:C00001]
Product
cutin monomer [CPD:C07300]
Comment
Cutin, a polymeric structural component of plant cuticles, is a polymer of hydroxy fatty acids that are usually C16 or C18 and contain up to three hydroxy groups. The enzyme from several fungal sources also hydrolyses the p-nitrophenyl esters of hexadecanoic acid. It is however inactive towards several esters that are substrates for non-specific esterases.
History
EC 3.1.1.74 created 2000
Orthology
K08095  cutinase
Genes
SMP: SMAC_04107
PAN: PODANS72p326 PODANSg09322 PODANSg3998
TTT: THITE_2120373
MTM: MYCTH_2110987
CTHR: CTHT_0064000
MGR: MGG_00734 MGG_01943 MGG_05798 MGG_09100 MGG_11966
FGR: FGSG_02342 FGSG_02890 FGSG_03457 FGSG_10634
FPU: FPSE_00693 FPSE_03781 FPSE_06675 FPSE_10277
FVR: FVEG_03395 FVEG_12346 FVEG_13638
FOX: FOXG_12155 FOXG_13189 FOXG_16606
CMT: CCM_06186
ANG: ANI_1_1504094(An11g00110) ANI_1_330124(An14g02170)
ZTR: MYCGRDRAFT_68483(MgCUT2) MYCGRDRAFT_77282(MgCUT1)
ABP: AGABI1DRAFT110999(AGABI1DRAFT_110999) AGABI1DRAFT111001(AGABI1DRAFT_111001) AGABI1DRAFT117924(AGABI1DRAFT_117924) AGABI1DRAFT89187(AGABI1DRAFT_89187)
ABV: AGABI2DRAFT176382(AGABI2DRAFT_176382) AGABI2DRAFT183005(AGABI2DRAFT_183005) AGABI2DRAFT190200(AGABI2DRAFT_190200) AGABI2DRAFT190202(AGABI2DRAFT_190202)
MTU: Rv1984c(cfp21) Rv2301(cut2) Rv3451(cut3)
MRA: MRA_1996(cfp21) MRA_2318(cut2) MRA_3492(cut3)
MTUR: CFBS_2090(cfp21) CFBS_2430(cut2) CFBS_3669(cut3)
MTO: MTCTRI2_2017(cfp21) MTCTRI2_2336(cut2) MTCTRI2_3519(cut3)
MTD: UDA_1984c(cfp21) UDA_2301(cut2) UDA_3451(cut3)
MTN: ERDMAN_2184(cfp21) ERDMAN_2516(cut2) ERDMAN_3780(cut3)
MTUT: HKBT1_2086(cfp21) HKBT1_2421(cut2) HKBT1_3655(cut3)
MTUU: HKBT2_2088(cfp21) HKBT2_2423(cut2) HKBT2_3663(cut3)
MTQ: HKBS1_2091(cfp21) HKBS1_2427(cut2) HKBS1_3666(cut3)
MBO: BQ2027_MB2006C(cfp21) BQ2027_MB2323(cut2) BQ2027_MB3481(cut3)
MBB: BCG_2317(cut2) BCG_3517(cut3)
MBT: JTY_1995(cfp21) JTY_2311(cut2) JTY_3517(cut3)
MBM: BCGMEX_2305(cut2) BCGMEX_3515(cut3)
MAF: MAF_19950(cfp21) MAF_23080(cut2) MAF_34660(cut3)
MCE: MCAN_20041(cfp21) MCAN_23271(cut2) MCAN_34681(cut3)
MCQ: BN44_40266(cfp) BN44_50253(cut) BN44_80127(cut)
MCV: BN43_31148(cfp) BN43_31550(cut) BN43_70119(cut)
MCX: BN42_30281(cfp) BN42_40220(cut) BN42_50129(cut)
MCZ: BN45_50259(cfp) BN45_50637(cut) BN45_70108(cut)
MSG: MSMEI_1491(cut2) MSMEI_1492(cut2) MSMEI_1493(cut4) MSMEI_2048(cut3)
MUL: MUL_0856(cut3)
MMI: MMAR_1098(cut3) MMAR_2908 MMAR_2934(cfp21)
CTER: A606_03065
RHB: NY08_3805
RFA: A3L23_01925(cut3_1)
RHS: A3Q41_01440(cut3)
RHU: A3Q40_01228(cut3)
GBR: Gbro_4300
SRT: Srot_0144
SFA: Sfla_1465
SVE: SVEN_7166
STRP: F750_5409
SFI: SFUL_5802
CFL: Cfla_3117
KRA: Krad_4111
ACTN: L083_4737
AFS: AFR_20835
 » show all
Taxonomy
Reference
1  [PMID:9281862]
  Authors
Garcia-Lepe R, Nuero OM, Reyes F, Santamaria F.
  Title
Lipases in autolysed cultures of filamentous fungi.
  Journal
Lett. Appl. Microbiol. 25 (1997) 127-30.
Reference
2  [PMID:1156575]
  Authors
Purdy RE, Kolattukudy PE.
  Title
Hydrolysis of plant cuticle by plant pathogens. Purification, amino acid composition, and molecular weight of two isozymes of cutinase and a nonspecific esterase from Fusarium solani f. pisi.
  Journal
Biochemistry. 14 (1975) 2824-31.
Reference
3  [PMID:239740]
  Authors
Purdy RE, Kolattukudy PE.
  Title
Hydrolysis of plant cuticle by plant pathogens. Properties of cutinase I, cutinase II, and a nonspecific esterase isolated from Fusarium solani pisi.
  Journal
Biochemistry. 14 (1975) 2832-40.
Other DBs
ExplorEnz - The Enzyme Database: 3.1.1.74
IUBMB Enzyme Nomenclature: 3.1.1.74
ExPASy - ENZYME nomenclature database: 3.1.1.74
BRENDA, the Enzyme Database: 3.1.1.74
CAS: 51377-41-4

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