KEGG   ENZYME: 3.1.1.74Help
Entry
EC 3.1.1.74                 Enzyme                                 

Name
cutinase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
cutin hydrolase
Reaction(IUBMB)
cutin + H2O = cutin monomers [RN:R05793]
Reaction(KEGG)
Substrate
cutin [CPD:C07299];
H2O [CPD:C00001]
Product
cutin monomer [CPD:C07300]
Comment
Cutin, a polymeric structural component of plant cuticles, is a polymer of hydroxy fatty acids that are usually C16 or C18 and contain up to three hydroxy groups. The enzyme from several fungal sources also hydrolyses the p-nitrophenyl esters of hexadecanoic acid. It is however inactive towards several esters that are substrates for non-specific esterases.
History
EC 3.1.1.74 created 2000
Orthology
K08095  
cutinase
Genes
MGR: 
ANI: 
NFI: 
AFM: 
AOR: 
AOR_1_1142054(AO090011000665)
ANG: 
ANI_1_1504094(An11g00110)
AFV: 
PCS: 
PIF: 
MTU: 
Rv1984c(cfp21) Rv2301(cut2) Rv3451(cut3)
MTC: 
MRA: 
MRA_1996(cfp21) MRA_2318(cut2) MRA_3492(cut3)
MTF: 
MTB: 
MBO: 
Mb2006c(cfp21) Mb2323(cut2) Mb3481(cut3)
MBB: 
BCG_2317(cut2) BCG_3517(cut3)
MBT: 
JTY_1995(cfp21) JTY_2311(cut2) JTY_3517(cut3)
MPA: 
MAV: 
MSM: 
MUL: 
MUL_0856(cut3)
MVA: 
MGI: 
MSP: 
MAB: 
MMC: 
MKM: 
MJL: 
MMI: 
RHA: 
GBR: 
SRT: 
CFL: 
TCU: 
KRA: 
 » show all
Taxonomy
Reference
1  [PMID:9281862]
  Authors
Garcia-Lepe R, Nuero OM, Reyes F, Santamaria F.
  Title
Lipases in autolysed cultures of filamentous fungi.
  Journal
Lett. Appl. Microbiol. 25 (1997) 127-30.
  Organism
Aspergillus nidulans [GN:ani], Fusarium decemcellulare, Fusarium moniliforme, Fusarium oxysporum, Fusarium semitectum
Reference
2  [PMID:1156575]
  Authors
Purdy RE, Kolattukudy PE.
  Title
Hydrolysis of plant cuticle by plant pathogens. Purification, amino acid composition, and molecular weight of two isozymes of cutinase and a nonspecific esterase from Fusarium solani f. pisi.
  Journal
Biochemistry. 14 (1975) 2824-31.
  Organism
Fusarium solani
Reference
3  [PMID:239740]
  Authors
Purdy RE, Kolattukudy PE.
  Title
Hydrolysis of plant cuticle by plant pathogens. Properties of cutinase I, cutinase II, and a nonspecific esterase isolated from Fusarium solani pisi.
  Journal
Biochemistry. 14 (1975) 2832-40.
  Organism
Fusarium solani
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
51377-41-4

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