KEGG   ENZYME: 3.1.1.94Help
Entry
EC 3.1.1.94                 Enzyme                                 

Name
versiconal hemiacetal acetate esterase;
VHA esterase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
versiconal-hemiacetal-acetate O-acetylhydrolase
Reaction(IUBMB)
(1) versiconal hemiacetal acetate + H2O = versiconal + acetate [RN:R10401];
(2) versiconol acetate + H2O = versiconol + acetate [RN:R10398]
Reaction(KEGG)
Substrate
versiconal hemiacetal acetate [CPD:C20505];
H2O [CPD:C00001];
versiconol acetate [CPD:C20506]
Product
versiconal [CPD:C20507];
acetate [CPD:C00033];
versiconol [CPD:C20508]
Comment
Isolated from the mold Aspergillus parasiticus. Involved in a metabolic grid that leads to aflatoxin biosynthesis.
History
EC 3.1.1.94 created 2013
Pathway
ec00254  Aflatoxin biosynthesis
Orthology
K17648  versiconal hemiacetal acetate esterase
Genes
PAN: PODANSg8561
MTM: MYCTH_54712
FGR: FGSG_09112
FVR: FVEG_03630 FVEG_07643
FOX: FOXG_04573 FOXG_05758
NHE: NECHADRAFT_44040
MAJ: MAA_10075
SSL: SS1G_01703
MBE: MBM_02254
PSCO: LY89DRAFT_594986
ANG: ANI_1_1088094(An11g08610)
PTE: PTT_13757
 » show all
Taxonomy
Reference
1  [PMID:8776851]
  Authors
Kusumoto K, Hsieh DP
  Title
Purification and characterization of the esterases involved in aflatoxin biosynthesis in Aspergillus parasiticus.
  Journal
Can. J. Microbiol. 42 (1996) 804-10.
Reference
2  [PMID:15184162]
  Authors
Chang PK, Yabe K, Yu J
  Title
The Aspergillus parasiticus estA-encoded esterase converts versiconal hemiacetal  acetate to versiconal and versiconol acetate to versiconol in aflatoxin biosynthesis.
  Journal
Appl. Environ. Microbiol. 70 (2004) 3593-9.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.1.1.94
IUBMB Enzyme Nomenclature: 3.1.1.94
ExPASy - ENZYME nomenclature database: 3.1.1.94
BRENDA, the Enzyme Database: 3.1.1.94

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