KEGG   ENZYME: 3.1.2.17Help
Entry
EC 3.1.2.17                 Enzyme                                 

Name
(S)-methylmalonyl-CoA hydrolase;
D-methylmalonyl-coenzyme A hydrolase
Class
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
BRITE hierarchy
Sysname
(S)-methylmalonyl-CoA hydrolase
Reaction(IUBMB)
(S)-methylmalonyl-CoA + H2O = methylmalonate + CoA [RN:R02764]
Reaction(KEGG)
Substrate
(S)-methylmalonyl-CoA [CPD:C00683];
H2O [CPD:C00001]
Product
methylmalonate [CPD:C02170];
CoA [CPD:C00010]
History
EC 3.1.2.17 created 1989
Pathway
Valine, leucine and isoleucine degradation
Propanoate metabolism
Reference
1  [PMID:6885824]
  Authors
Kovachy RJ, Copley SD, Allen RH.
  Title
Recognition, isolation, and characterization of rat liver D-methylmalonyl coenzyme A hydrolase.
  Journal
J. Biol. Chem. 258 (1983) 11415-21.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
87928-03-8

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