KEGG   ENZYME: 3.1.2.25Help
Entry
EC 3.1.2.25                 Enzyme                                 

Name
phenylacetyl-CoA hydrolase
Class
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
BRITE hierarchy
Sysname
phenylglyoxylyl-CoA hydrolase
Reaction(IUBMB)
phenylglyoxylyl-CoA + H2O = phenylglyoxylate + CoA [RN:R07294]
Reaction(KEGG)
Substrate
phenylglyoxylyl-CoA [CPD:C15524];
H2O [CPD:C00001]
Product
phenylglyoxylate [CPD:C02137];
CoA [CPD:C00010]
Comment
This is the second step in the conversion of phenylacetyl-CoA to phenylglyoxylate, the first step being carried out by EC 1.17.5.1, phenylacetyl-CoA dehydrogenase.
History
EC 3.1.2.25 created 2004
Pathway
Phenylalanine metabolism
Orthology
K18361  
phenylacetyl-CoA:acceptor oxidoreductase
Genes
EBA: 
ebA5393(padB)
AZO: 
azo1946(padB)
AZA: 
AZKH_2904(padB)
TMZ: 
RPD: 
MAG: 
Taxonomy
Reference
1  [PMID:10336636]
  Authors
Rhee SK, Fuchs G.
  Title
Phenylacetyl-CoA:acceptor oxidoreductase, a membrane-bound molybdenum-iron-sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica.
  Journal
Eur. J. Biochem. 262 (1999) 507-15.
Reference
2  [PMID:9575237]
  Authors
Schneider S, Fuchs G.
  Title
Phenylacetyl-CoA:acceptor oxidoreductase, a new alpha-oxidizing enzyme that produces phenylglyoxylate. Assay, membrane localization, and differential production in Thauera aromatica.
  Journal
Arch. Microbiol. 169 (1998) 509-16.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
57219-72-4

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