KEGG   ENZYME: 3.1.2.26Help
Entry
EC 3.1.2.26                 Enzyme                                 

Name
bile-acid-CoA hydrolase
Class
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
BRITE hierarchy
Sysname
deoxycholoyl-CoA hydrolase
Reaction(IUBMB)
deoxycholoyl-CoA + H2O = CoA + deoxycholate [RN:R07295]
Reaction(KEGG)
Substrate
deoxycholoyl-CoA [CPD:C15560];
H2O [CPD:C00001]
Product
CoA [CPD:C00010];
deoxycholate [CPD:C04483]
Comment
Choloyl-CoA, 3-dehydrocholoyl-CoA and chenodeoxycholoyl-CoA can also act as substrates, but acetyl-CoA, isovaleryl-CoA, palmitoyl-CoA and phenylacetyl-CoA cannot.
History
EC 3.1.2.26 created 2005
Pathway
Secondary bile acid biosynthesis
Orthology
K15871  
bile acid-CoA hydrolase
Reference
1  [PMID:9869646]
  Authors
Ye HQ, Mallonee DH, Wells JE, Bjorkhem I, Hylemon PB.
  Title
The bile acid-inducible baiF gene from Eubacterium sp. strain VPI 12708 encodes a bile acid-coenzyme A hydrolase.
  Journal
J. Lipid. Res. 40 (1999) 17-23.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
220983-07-3

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