KEGG   ENZYME: 3.1.2.5Help
Entry
EC 3.1.2.5                  Enzyme                                 

Name
hydroxymethylglutaryl-CoA hydrolase;
beta-hydroxy-beta-methylglutaryl coenzyme A hydrolase;
beta-hydroxy-beta-methylglutaryl coenzyme A deacylase;
hydroxymethylglutaryl coenzyme A hydrolase;
hydroxymethylglutaryl coenzyme A deacylase;
3-hydroxy-3-methylglutaryl-CoA hydrolase
Class
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
BRITE hierarchy
Sysname
(S)-3-hydroxy-3-methylglutaryl-CoA hydrolase
Reaction(IUBMB)
(S)-3-hydroxy-3-methylglutaryl-CoA + H2O = CoA + 3-hydroxy-3-methylglutarate [RN:R02083]
Reaction(KEGG)
Substrate
(S)-3-hydroxy-3-methylglutaryl-CoA [CPD:C00356];
H2O [CPD:C00001]
Product
CoA [CPD:C00010];
3-hydroxy-3-methylglutarate [CPD:C03761]
History
EC 3.1.2.5 created 1961
Reference
1  [PMID:13563516]
  Authors
DEKKER EE, SCHLESINGER MJ, COON MJ.
  Title
beta-Hydroxy-beta-methylglutaryl coenzyme A deacylase.
  Journal
J. Biol. Chem. 233 (1958) 434-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9025-89-2

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