| Entry |
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|---|
| Name |
deoxyribonuclease IV;
deoxyribonuclease IV (phage-T4-induced) (misleading);
endodeoxyribonuclease IV (phage T4-induced) (misleading);
E. coli endonuclease IV;
endodeoxyribonuclease (misleading);
redoxyendonuclease;
deoxriboendonuclease (misleading);
endonuclease II;
endonuclease IV;
DNA-adenine-transferase;
nfo (gene name)
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| Class |
Hydrolases;
Acting on ester bonds;
Endodeoxyribonucleases producing 5'-phosphomonoesters
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|---|
| Reaction(IUBMB) |
Endonucleolytic cleavage of ssDNA at apurinic/apyrimidinic sites to 5'-phosphooligonucleotide end-products
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| Comment |
The enzyme is an apurinic/apyrimidinic (AP) site endonuclease that primes DNA repair synthesis at AP sites. It specifically cleaves the DNA backbone at AP sites and also removes 3' DNA-blocking groups such as 3' phosphates, 3' phosphoglycolates, and 3' alpha,beta-unsaturated aldehydes that arise from oxidative base damage and the activity of combined glycosylase/lyase enzymes. It is also the only known repair enzyme that is able to cleave the DNA backbone 5' of the oxidative lesion alpha-deoxyadenosine. The enzyme has a strong preference for single-stranded DNA.
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| History |
EC 3.1.21.2 created 1972 as EC 3.1.4.30, transferred 1978 to EC 3.1.21.2, modified 2014
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| Orthology |
| deoxyribonuclease IV | | endonuclease I |
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| Genes |
ECU: | | EIN: | | EHE: | | ERO: | | NCE: | | ECO: | | ECJ: | | ECD: | | EBW: | | ECOK: | | ECE: | | ECS: | | ECF: | | ETW: | | ELX: | | EOJ: | | EOI: | | EOH: | | ECG: | | EOK: | | ELR: | | ECC: | | ECP: | | ECI: | | ECV: | | ECX: | | ECW: | | ECM: | | ECY: | | ECR: | | ECQ: | | ECK: | | ECT: | | EOC: | | EUM: | | ECZ: | | ELO: | | ELN: | | ELH: | | ESE: | | ESO: | | ESM: | | ESL: | | ECL: | | EBR: | | EBD: | | EKO: | | EKF: | | EAB: | | EDH: | | EDJ: | | EIH: | | ENA: | | ELU: | | EUN: | | ELW: | | ELL: | | ELC: | | ELD: | | ELP: | | EBL: | | EBE: | | ELF: | | ECOA: | | ECOL: | | ECOI: | | ECOJ: | | ECOO: | | ECOH: | | ECOS: | | EFE: | | EAL: | | STY: | | STT: | | SEX: | | SENT: | | STM: | | SEO: | | SEV: | | SEY: | | SEM: | | SEJ: | | SEB: | | SEF: | | SETU: | | SETC: | | SENR: | | SEND: | | SENI: | | SEEN: | | SPT: | | SEK: | | SPQ: | | SEI: | | SEC: | | SEH: | | SHB: | | SENH: | | SEEH: | | SEE: | | SENN: | | SEW: | | SEA: | | SENS: | | SED: | | SEG: | | SEL: | | SEGA: | | SET: | | SENA: | | SENO: | | SENV: | | SENQ: | | SENL: | | SENJ: | | SEEC: | | SEEB: | | SEEP: | | SENB: | | SENE: | | SENC: | | SES: | | SBG: | | SBZ: | | SBV: | | SFL: | | SFX: | | SFV: | | SFE: | | SFN: | | SFS: | | SFT: | | SSN: | | SBO: | | SBC: | | SDY: | | SDZ: | | SHQ: | | ENT: | | ENC: | | ENO: | | EEC: | | ENL: | | ECLG: | | ECLE: | | ECLN: | | ECLI: | | ECLX: | | ECLY: | | ECLZ: | | ECLA: | | ECLC: | | ESC: | | KLE: | | EAS: | | EAU: | | EHM: | | EKB: | | ELG: | | EXF: | | ECLS: | | ENR: | | ENX: | | ENF: | | ESA: | | CSK: | | CSZ: | | CSI: | | CSJ: | | CCON: | | CDM: | | CMJ: | | CUI: | | CMW: | | CTU: | | KPN: | | KPU: | | KPM: | | KPP: | | KPK: | | KPH: | | KPZ: | | KPV: | | KPW: | | KPY: | | KPG: | | KPC: | | KPQ: | | KPT: | | KPE: | | KPO: | | KPR: | | KPJ: | | KPI: | | KPA: | | KPS: | | KPX: | | KPB: | | KPNE: | | KPNU: | | KVA: | | KVD: | | KVQ: | | KOX: | | KOE: | | KOY: | | KMI: | | KOK: | | KOC: | | KOM: | | KQU: | | EAE: | | EAR: | | CKO: | | CRO: | | CFD: | | CBRA: | | CAMA: | | CIF: | | CFAR: | | SECT: | | EBT: | | ROR: | | RON: | | CNT: | | CEM: | | CEN: | | CED: | | PGE: | | KSA: | | KOR: | | KRD: | | KCO: | | KIN: | | KGO: | | LAX: | | LAZ: | | LEF: | | EBF: | | PSTS: | | YPE: | | YPK: | | YPA: | | YPN: | | YPM: | | YPP: | | YPG: | | YPZ: | | YPT: | | YPD: | | YPX: | | YPH: | | YPW: | | YPJ: | | YPV: | | YPL: | | YPS: | | YPO: | | YPI: | | YPY: | | YPB: | | YPQ: | | YPU: | | YPR: | | YPC: | | YPF: | | YEN: | | YEP: | | YEY: | | YEL: | | YEW: | | YET: | | YEF: | | YEE: | | YSI: | | YAL: | | YFR: | | YIN: | | YKR: | | YRO: | | YRU: | | YRB: | | YAK: | | SPE: | | SRR: | | SRL: | | SRY: | | SPLY: | | SRS: | | SRA: | | SSZ: | | SMAF: | | SMW: | | SMAR: | | SMAC: | | SLQ: | | SERF: | | SERS: | | SFW: | | SFG: | | SRZ: | | SFO: | | RAH: | | RAQ: | | RAA: | | ECA: | | PATR: | | PATO: | | PCT: | | PCC: | | PCV: | | PWA: | | PPAR: | | PEC: | | PWS: | | SOD: | | PES: | | DDA: | | DDD: | | DZE: | | DDC: | | DZC: | | DSO: | | ETA: | | EPY: | | EPR: | | EAM: | | EAY: | | EBI: | | ERJ: | | EGE: | | BUC: | | BAP: | | BAU: | | BAW: | | BAJC: | | BUA: | | BUP: | | BAK: | | BUH: | | BAPF: | | BAPG: | | BAPU: | | BAPW: | | BAS: | | BAB: | | BCC: | | BAJ: | | BAPH: | | PAM: | | PLF: | | PAJ: | | PAQ: | | PVA: | | PAO: | | KLN: | | PANT: | | PANP: | | HHS: | | PCK: | | PAGG: | | PAGC: | | PSTW: | | PALH: | | TCI: | | PLU: | | PAY: | | PTT: | | PMR: | | PMIB: | | PVL: | | XBO: | | XBV: | | XNE: | | XNM: | | XDO: | | XPO: | | XHO: | | PSI: | | PSX: | | PSTA: | | PRG: | | MMK: | | EIC: | | ETR: | | ETD: | | ETE: | | ETC: | | EDW: | | EDL: | | EHO: | | HAV: | | OPO: | | PFQ: | | PSHI: | | HDU: | | HAP: | | HPAZ: | | HPAS: | | HPAK: | | MHT: | | MHQ: | | MHAT: | | MHX: | | MHAE: | | MHAM: | | MHAO: | | MHAL: | | MHAQ: | | MHAY: | | MVR: | | MVI: | | MVG: | | MVE: | | APL: | | APJ: | | APA: | | ASI: | | ASS: | | AEU: | | GAN: | | BTO: | | BTRE: | | BTRH: | | BTRA: | | VCH: | | VCF: | | VCE: | | VCJ: | | VCO: | | VCR: | | VCM: | | VCI: | | VCL: | | VCQ: | | VCS: | | VCX: | | VCZ: | | VVU: | | VVY: | | VVM: | | VVL: | | VPA: | | VPB: | | VPK: | | VPF: | | VPH: | | VHA: | | VCA: | | VAG: | | VEX: | | VHR: | | VNA: | | VOW: | | VSP: | | VEJ: | | VFU: | | VNI: | | VAN: | | LAG: | | VAU: | | VCY: | | VCT: | | VFL: | | VMI: | | VBR: | | VSC: | | VGA: | | VSH: | | VFI: | | VFM: | | VSA: | | AWD: | | PPR: | | PGB: | | PDS: | | GHO: | | SLO: | | SSE: | | SPL: | | SHL: | | SWD: | | SWP: | | SVO: | | PSY: | | FBL: | | MVS: | | TEE: | | AEH: | | HHA: | | HCS: | | HAK: | | HAM: | | HCO: | | HALO: | | HAA: | | KUS: | | KMA: | | AHA: | | AHY: | | AHD: | | AHR: | | AHP: | | AHJ: | | AHH: | | AHI: | | ASA: | | AVR: | | AVO: | | AMED: | | ASR: | | AAJ: | | AEO: | | TAU: | | GAP: | | FPP: | | SEDS: | | BCI: | | BCIB: | | BCIG: | | OFO: | | WSU: | | TDN: | | SUA: | | SKU: | | SULR: | | CFF: | | CFT: | | CFV: | | CFX: | | CFZ: | | CAMP: | | CFP: | | CCV: | | CHA: | | CCOC: | | CAJ: | | CGRA: | | CURE: | | CHYO: | | CSPF: | | CPIN: | | ABU: | | ABT: | | ABL: | | ANT: | | ARC: | | ALP: | | SDL: | | SBA: | | SMUL: | | SHAL: | | SULS: | | NSA: | | NIS: | | SUN: | | SLH: | | NAM: | | GSU: | | GSK: | | GME: | | GUR: | | GLO: | | GBM: | | GEO: | | GEM: | | GEB: | | GPI: | | GAO: | | PCA: | | PPD: | | PACE: | | PEF: | | DES: | | DEU: | | DVU: | | DVL: | | DVM: | | DVG: | | DDE: | | DDN: | | DMA: | | DSA: | | DAF: | | DHY: | | DAS: | | DPI: | | DEJ: | | DBA: | | DRT: | | DPS: | | DAK: | | DPR: | | DSF: | | DOL: | | DML: | | DAT: | | DTO: | | ADE: | | ACP: | | AFW: | | ANK: | | CCX: | | SUR: | | AGE: | | SCL: | | SCU: | | DAO: | | SFU: | | DBR: | | HMR: | | DAV: | | DPB: | | BMX: | | BJA: | | RPC: | | MGM: | | BSU: | | BSR: | | BSL: | | BSH: | | BSY: | | BSUT: | | BSUL: | | BSUS: | | BSS: | | BST: | | BSO: | | BSN: | | BSQ: | | BSX: | | BSP: | | BLI: | | BLD: | | BLH: | | BAY: | | BAQ: | | BYA: | | BAMP: | | BAML: | | BAMA: | | BAMN: | | BAMB: | | BAMT: | | BAMY: | | BMP: | | BAO: | | BAZ: | | BQL: | | BXH: | | BQY: | | BAMI: | | BAMC: | | BAMF: | | BAE: | | BATR: | | BVM: | | BHA: | | BAN: | | BAR: | | BAT: | | BAH: | | BAI: | | BAX: | | BANT: | | BANR: | | BANS: | | BANH: | | BANV: | | BCE: | | BCA: | | BCZ: | | BCR: | | BCB: | | BCU: | | BCG: | | BCQ: | | BCX: | | BAL: | | BNC: | | BCF: | | BCER: | | BCY: | | BTK: | | BTL: | | BTB: | | BTT: | | BTHR: | | BTHI: | | BTC: | | BTF: | | BTM: | | BTG: | | BTI: | | BTN: | | BTHT: | | BTHU: | | BTW: | | BTHY: | | BWE: | | BWW: | | BTY: | | BMYC: | | BMYO: | | BCL: | | BPU: | | BPUM: | | BPUS: | | BPF: | | BMQ: | | BMD: | | BMH: | | BMEG: | | BCO: | | BCK: | | BAG: | | BCOA: | | BJS: | | BACI: | | BIF: | | BLE: | | BMET: | | GST: | | BACW: | | BACP: | | BACB: | | BBY: | | BACO: | | BACY: | | BACL: | | BALM: | | BEO: | | BSM: | | BSJ: | | BON: | | BGY: | | BFX: | | BGI: | | BWH: | | BXI: | | BHK: | | BKW: | | OIH: | | GKA: | | GTE: | | GTK: | | GTN: | | GWC: | | GYC: | | GYA: | | GCT: | | GMC: | | GGH: | | GJF: | | GEA: | | GEL: | | GSE: | | GSR: | | GEJ: | | GTH: | | PTL: | | AFL: | | AGN: | | ANM: | | AAMY: | | ANL: | | AXL: | | LSP: | | LGY: | | LFU: | | HHD: | | HMN: | | TAP: | | VIR: | | VHL: | | VIG: | | VIL: | | VNE: | | LAO: | | FPN: | | FAR: | | SJE: | | APAK: | | BSE: | | SAU: | | SAV: | | SAW: | | SAH: | | SAJ: | | SAM: | | SAS: | | SAR: | | SAC: | | SAX: | | SAA: | | SAO: | | SAE: | | SAD: | | SUU: | | SUV: | | SUE: | | SUJ: | | SUK: | | SUC: | | SUT: | | SUQ: | | SUZ: | | SUD: | | SUX: | | SUW: | | SUG: | | SUF: | | SAUA: | | SAUE: | | SAUN: | | SAUS: | | SAUU: | | SAUG: | | SAUZ: | | SAUT: | | SAUJ: | | SAUK: | | SAUQ: | | SAUV: | | SAUW: | | SAUX: | | SAUY: | | SAB: | | SUY: | | SAUB: | | SAUM: | | SAUC: | | SAUR: | | SAUI: | | SAUD: | | SAUF: | | SAMS: | | SUH: | | SEP: | | SER: | | SEPP: | | SEPS: | | SHA: | | SHH: | | SSP: | | SCA: | | SLG: | | SLN: | | SSD: | | SDT: | | SWA: | | SPAS: | | SXY: | | SXL: | | SXO: | | SHU: | | SCAP: | | SSCH: | | SSCZ: | | SAGQ: | | SEQO: | | SSIF: | | SCV: | | SPET: | | SLZ: | | SCOH: | | MCL: | | MCAK: | | SHV: | | SBAC: | | LMO: | | LMF: | | LMH: | | LMC: | | LMN: | | LMY: | | LMT: | | LMG: | | LMS: | | LMJ: | | LMQ: | | LML: | | LMP: | | LMW: | | LMX: | | LMZ: | | LMON: | | LMOC: | | LMOS: | | LMOO: | | LMOY: | | LMOT: | | LMOA: | | LMOL: | | LMOG: | | LMOE: | | LMOB: | | LMOJ: | | LMOZ: | | LMOD: | | LMOW: | | LMOX: | | LMOQ: | | LMR: | | LMOK: | | LMV: | | LMOM: | | LIN: | | LWE: | | LSG: | | LIV: | | LII: | | LIW: | | LIA: | | LIO: | | ESI: | | EAT: | | EAN: | | EXM: | | EXU: | | GOT: | | BBE: | | BLR: | | BFM: | | PJD: | | GYM: | | PPY: | | PPM: | | PPO: | | PPOL: | | PPQ: | | PPOY: | | PMS: | | PMQ: | | PMW: | | PTA: | | PLV: | | PSAB: | | PDU: | | PBD: | | PGM: | | POD: | | PAEN: | | PAEF: | | PAEQ: | | PSTE: | | PAEA: | | PAEE: | | PAEH: | | PAEJ: | | PBJ: | | PIH: | | PRI: | | PPEO: | | PNP: | | POW: | | PBV: | | PXL: | | PYG: | | PSWU: | | PDH: | | TCO: | | ANX: | | AAC: | | AAD: | | BTS: | | TUM: | | TAB: | | SIV: | | SSIL: | | PLN: | | PKU: | | PRT: | | PLL: | | PANA: | | PDG: | | PHC: | | PMAR: | | PPLA: | | PFAE: | | JEO: | | KUR: | | SPSY: | | SPOR: | | SPOP: | | SURE: | | RST: | | NTR: | | LPL: | | LPJ: | | LPT: | | LPS: | | LPR: | | LPZ: | | LPB: | | LSA: | | LBR: | | LBK: | | LCA: | | LPQ: | | LPI: | | LPAP: | | LCB: | | LCZ: | | LCS: | | LCE: | | LCW: | | LCL: | | LCX: | | LRH: | | LRG: | | LRL: | | LRA: | | LRO: | | LRC: | | LBH: | | LBN: | | LRM: | | LSN: | | LHO: | | LMU: | | LGN: | | LKO: | | LHI: | | LKU: | | LPX: | | LPAR: | | LLE: | | LPD: | | LCU: | | LCT: | | LBT: | | LCV: | | LAH: | | PPE: | | PPEN: | | PCE: | | PDM: | | PACI: | | EFA: | | EFL: | | EFI: | | EFD: | | EFS: | | EFN: | | EFQ: | | EFC: | | EFAU: | | EFU: | | EFM: | | EFT: | | EHR: | | ENE: | | ECAS: | | EMU: | | EDU: | | EGA: | | ESS: | | MPS: | | MPX: | | THL: | | VTE: | | VPI: | | CRN: | | CML: | | CAW: | | CARC: | | MARR: | | JEP: | | JDA: | | CAC: | | CAE: | | CAY: | | CPE: | | CPF: | | CPR: | | CTC: | | CTET: | | CNO: | | CBO: | | CBA: | | CBH: | | CBY: | | CBL: | | CBK: | | CBB: | | CBI: | | CBN: | | CBT: | | CBF: | | CBM: | | CBJ: | | CBE: | | CBZ: | | CBEI: | | CKL: | | CKR: | | CLJ: | | CCB: | | CLS: | | CLB: | | CSR: | | CPAS: | | CPAT: | | CPAE: | | CSB: | | CAH: | | CLT: | | CBV: | | CSQ: | | CLD: | | CACE: | | CCK: | | CBUT: | | CTYK: | | CEU: | | CTAE: | | CFM: | | AOE: | | ASF: | | ASM: | | ASO: | | ASB: | | GFE: | | CTX: | | CCE: | | CCL: | | ESR: | | ESU: | | CSS: | | CSD: | | CCEL: | | EHA: | | RBR: | | RUM: | | RUS: | | RBP: | | BFI: | | CLE: | | RHO: | | RIX: | | RIM: | | CCT: | | ROB: | | BYL: | | RTO: | | CPY: | | LACY: | | CSH: | | CSO: | | BPRL: | | CPRO: | | ERE: | | ERT: | | ERA: | | CDF: | | PDC: | | CDC: | | CDL: | | PDF: | | EAC: | | STH: | | SLP: | | DSY: | | DHD: | | DDH: | | DDL: | | DMT: | | DRM: | | DAE: | | DCA: | | DKU: | | DRU: | | DGI: | | DFG: | | PTH: | | DAU: | | TJR: | | SGY: | | DOR: | | DAI: | | DMI: | | DED: | | DEC: | | DRS: | | HMO: | | EEL: | | ELM: | | AWO: | | OVA: | | TMR: | | SAY: | | SAP: | | CAD: | | IBU: | | FPLA: | | BPRM: | | BPRS: | | TTE: | | TEX: | | THX: | | TPD: | | TIT: | | TMT: | | TBO: | | TWI: | | TKI: | | CHY: | | MTA: | | ADG: | | TPZ: | | CSC: | | ATE: | | COB: | | CHD: | | COW: | | CKI: | | CKN: | | CLC: | | TOC: | | TTM: | | TTO: | | TXY: | | TSH: | | CPO: | | TNR: | | MAS: | | NTH: | | HOR: | | HAS: | | HPK: | | AAR: | | HHL: | | FMA: | | PED: | | VPR: | | VAT: | | MED: | | SSG: | | SRI: | | PUF: | | PFT: | | AFN: | | AIN: | | ERH: | | ERS: | | ERL: | | TUR: | | FRO: | | ERB: | | LPIL: | | MGE: | | MGU: | | MGC: | | MGQ: | | MGX: | | MPN: | | MPM: | | MPJ: | | MPB: | | MPU: | | MPE: | | MGA: | | MGH: | | MGF: | | MGN: | | MGS: | | MGT: | | MGV: | | MGW: | | MGAC: | | MGAN: | | MGNC: | | MGZ: | | MMY: | | MMYM: | | MMYI: | | MML: | | MCP: | | MCAC: | | MCAP: | | MCAR: | | MCAI: | | MLC: | | MLH: | | MMO: | | MHY: | | MHJ: | | MHP: | | MHN: | | MHYL: | | MHYO: | | MSY: | | MSO: | | MAA: | | MAL: | | MAT: | | MCO: | | MHO: | | MHOM: | | MCD: | | MHR: | | MHH: | | MHM: | | MHS: | | MHV: | | MFR: | | MFM: | | MFP: | | MBV: | | MBH: | | MBI: | | MBQ: | | MHA: | | MHF: | | MSS: | | MSK: | | MPF: | | MPUT: | | MHE: | | MWE: | | MHL: | | MCY: | | MHB: | | MPV: | | MOV: | | MBC: | | MCR: | | MCM: | | MGJ: | | MFQ: | | MCAN: | | MYT: | | MDS: | | MCAS: | | MCK: | | MARG: | | UUR: | | UPA: | | UPR: | | UUE: | | HCR: | | POY: | | AYW: | | MBP: | | PML: | | PAL: | | NZS: | | PSOL: | | ACL: | | ABRA: | | APAL: | | AOC: | | MFL: | | MFW: | | SCR: | | SSYR: | | SDI: | | STAI: | | SAPI: | | SMIR: | | SMIA: | | SCQ: | | SSAB: | | SATR: | | SERI: | | STUR: | | SKN: | | SCJ: | | SHJ: | | SCK: | | MBJ: | | MTU: | | MTV: | | MTC: | | MRA: | | MTF: | | MTB: | | MTK: | | MTI: | | MTE: | | MTUR: | | MTL: | | MTO: | | MTD: | | MTN: | | MTJ: | | MTUB: | | MTUC: | | MTUE: | | MTX: | | MTUH: | | MTUL: | | MTUT: | | MTUU: | | MTQ: | | MBO: | | MBB: | | MBT: | | MBM: | | MBK: | | MBX: | | MBZ: | | MAF: | | MCE: | | MCQ: | | MCV: | | MCX: | | MCZ: | | MMIC: | | MLE: | | MLB: | | MPA: | | MAO: | | MAVI: | | MAVU: | | MAV: | | MAVD: | | MAVR: | | MAVA: | | MIT: | | MIA: | | MIE: | | MIR: | | MID: | | MYO: | | MCHI: | | MSM: | | MSG: | | MSB: | | MSN: | | MSH: | | MSA: | | MUL: | | MVA: | | MGI: | | MSP: | | MMC: | | MKM: | | MJL: | | MJD: | | MMI: | | MMAE: | | MRH: | | MMM: | | MCB: | | MLI: | | MKN: | | MKS: | | MKI: | | MNE: | | MYV: | | MYE: | | MGO: | | MFT: | | MHAD: | | MPHL: | | MVQ: | | MYN: | | MLL: | | ASD: | | NFA: | | NFR: | | NCY: | | NBR: | | NNO: | | NSL: | | NSR: | | RHA: | | ROP: | | ROA: | | REQ: | | RPY: | | RHB: | | RAV: | | RFA: | | RHW: | | RHS: | | GBR: | | GPO: | | GOR: | | GOQ: | | GTA: | | TPR: | | SCO: | | SMA: | | SGR: | | SGB: | | SCB: | | SSX: | | SVL: | | SCT: | | SCY: | | SFA: | | SBH: | | SHY: | | SHO: | | SVE: | | SDV: | | SALB: | | SALS: | | STRP: | | SFI: | | SCI: | | SRC: | | SALU: | | SALL: | | SLV: | | SGU: | | SVT: | | STRE: | | SCW: | | SLD: | | SXI: | | STRM: | | STRC: | | SAMB: | | SPRI: | | SCZ: | | SCX: | | SRW: | | STRF: | | SLE: | | SRN: | | SPAV: | | SLC: | | STRT: | | SCLF: | | SGS: | | STSI: | | SLS: | | SNR: | | SPLU: | | STRD: | | SNW: | | SAUO: | | KSK: | | KAB: | | KAU: | | BCV: | | LMOI: | | XCE: | | IVA: | | IDO: | | CET: | | CCEU: | | CFL: | | CFI: | | CGA: | | CEZ: | | ICA: | | SERJ: | | PAC: | | PAK: | | PAV: | | PAX: | | PAZ: | | PAW: | | PAD: | | PCN: | | PACC: | | PACH: | | PACN: | | CACN: | | PRA: | | PFR: | | PFRE: | | PRL: | | PPC: | | PBO: | | AACI: | | MPH: | | TFL: | | TFA: | | TES: | | TEZ: | | NCA: | | NDK: | | KFL: | | PSIM: | | TFU: | | NDA: | | NAL: | | NGV: | | TCU: | | SRO: | | NOA: | | ACE: | | NML: | | GOB: | | BSD: | | MMAR: | | SEN: | | SVI: | | AMD: | | AMN: | | AMM: | | AMZ: | | AOI: | | AJA: | | AMQ: | | ALU: | | PDX: | | PSEA: | | PSEE: | | PSEH: | | PSEQ: | | PECQ: | | PHH: | | AMI: | | SESP: | | KAL: | | KPHY: | | LED: | | AHM: | | ACTI: | | ACAD: | | AHG: | | ALL: | | PMAD: | | STP: | | SAQ: | | MAU: | | MIL: | | VMA: | | AMS: | | ASE: | | ACTN: | | AFS: | | CAI: | | SNA: | | BLO: | | BLJ: | | BLN: | | BLON: | | BLF: | | BLL: | | BLB: | | BLM: | | BLK: | | BLG: | | BLZ: | | BLX: | | BBI: | | BBP: | | BBF: | | BBV: | | BBRU: | | BBRE: | | BBRV: | | BBRJ: | | BBRC: | | BBRN: | | BBRS: | | BBRD: | | BSCA: | | TBI: | | AEY: | | ABAI: | | RXY: | | RRD: | | CWO: | | AFO: | | CCU: | | SHI: | | ELE: | | EYY: | | GPA: | | AEQ: | | DDT: | | APV: | | CGO: | | CBAC: | | MBF: | | DET: | | DEH: | | DEB: | | DEV: | | DEG: | | DMC: | | DMD: | | DMG: | | DMX: | | DMY: | | DMZ: | | DUC: | | DLY: | | DEW: | | DFO: | | RRS: | | RCA: | | CAU: | | CAG: | | CHL: | | HAU: | | TRO: | | STI: | | ATM: | | ABAO: | | CAP: | | TRA: | | TTH: | | TTJ: | | TTS: | | TTL: | | TSC: | | THC: | | TOS: | | TAQ: | | TPAR: | | TBC: | | MRB: | | MRE: | | MSV: | | OPR: | | MHD: | | CCZ: | | FGI: | | TTR: | | CTR: | | CTD: | | CTF: | | CTRD: | | CTRO: | | CTRT: | | CTA: | | CTY: | | CRA: | | CTRQ: | | CTRX: | | CTRZ: | | CTRP: | | CTLJ: | | CTLX: | | CTLL: | | CTB: | | CTRR: | | CTLF: | | CTLI: | | CTL: | | CTRU: | | CTRL: | | CTRV: | | CTRM: | | CTLA: | | CTLM: | | CTLS: | | CTLZ: | | CTLC: | | CTLN: | | CTLB: | | CTLQ: | | CTO: | | CTRN: | | CTJ: | | CTZ: | | CTG: | | CTK: | | CSW: | | CES: | | CTRB: | | CTRE: | | CTRS: | | CTEC: | | CFS: | | CFW: | | CTFW: | | CTRF: | | CTCH: | | CTN: | | CTQ: | | CTV: | | CTW: | | CTRG: | | CTRI: | | CTRA: | | CTRH: | | CTRJ: | | CTRK: | | CTJT: | | CTCF: | | CTFS: | | CTHF: | | CTCJ: | | CTHJ: | | CTMJ: | | CTTJ: | | CTJS: | | CTRC: | | CTRW: | | CTRY: | | CTCT: | | CMU: | | CMUR: | | CMN: | | CMM: | | CMG: | | CMX: | | CMZ: | | CPN: | | CPA: | | CPJ: | | CPT: | | CLP: | | CPM: | | CPEC: | | CPEO: | | CPER: | | CHP: | | CHB: | | CHS: | | CHI: | | CHT: | | CHC: | | CHR: | | CPSC: | | CPSN: | | CPSB: | | CPSG: | | CPSM: | | CPSI: | | CPSV: | | CPSW: | | CPST: | | CPSD: | | CPSA: | | CAV: | | CCA: | | CAB: | | CABO: | | CFE: | | CGZ: | | PCU: | | PNL: | | PUV: | | WCH: | | SNG: | | AMU: | | AGL: | | MIN: | | PSL: | | PIR: | | PLM: | | PBS: | | PLS: | | PLH: | | TTF: | | GES: | | IPA: | | SACI: | | PBOR: | | TBE: | | SSM: | | SFC: | | SBU: | | SGP: | | SLR: | | ABA: | | ACA: | | ACM: | | GMA: | | TSA: | | TRS: | | SUS: | | EPO: | | IPO: | | LBA: | | LEO: | | LOT: | | LEQ: | | STR: | | TAI: | | ACO: | | TLI: | | AMO: | | CPOR: | | FSU: | | FSC: | | GAU: | | GPH: | | GBA: | | BTH: | | BTHO: | | BFR: | | BFS: | | BFG: | | BFB: | | BVU: | | BHL: | | BXY: | | BDO: | | BDH: | | BOA: | | BCEL: | | BACC: | | PAH: | | PBT: | | PMUC: | | PDI: | | PARY: | | PARC: | | TFO: | | TOH: | | BVS: | | PSAC: | | OSP: | | AFD: | | ASH: | | RBC: | | BLQ: | | ASX: | | CHE: | | CTE: | | CPC: | | CLZ: | | CCH: | | CPH: | | CPB: | | CLI: | | PVI: | | PLT: | | PPH: | | PAA: | | PROC: | | PRS: | | PROS: | | MRO: | | AAE: | | HTH: | | HTE: | | TAL: | | SUL: | | SAF: | | PMX: | | TTK: | | TAM: | | DTE: | | TMA: | | TMM: | | TMI: | | TMW: | | TMQ: | | TMX: | | TPT: | | TRQ: | | TNA: | | TNP: | | THQ: | | THR: | | TLE: | | TTA: | | PHY: | | TME: | | TAF: | | THP: | | THER: | | FNO: | | FPE: | | FIA: | | PMO: | | MPZ: | | MARN: | | DTN: | | KOL: | | KPF: | | MPG: | | CEX: | | DIN: | | DDF: | | DAP: | | CNI: | | FSI: | | CABY: | | DTH: | | DTU: | | TYE: | | LFC: | | LFI: | | LFP: | | PRF: | | MOX: | | BGW: | | MJA: | | MFE: | | MVU: | | MFS: | | MIF: | | MJH: | | MIG: | | MMP: | | MMQ: | | MMX: | | MMZ: | | MMD: | | MMAK: | | MMAO: | | MAE: | | MVN: | | MVO: | | MOK: | | MAC: | | MBA: | | MBY: | | MBW: | | MBAR: | | MBAK: | | MMA: | | MMAZ: | | MMJ: | | MMAC: | | MVC: | | MEK: | | MLS: | | METM: | | MEF: | | MEQ: | | MSJ: | | MSZ: | | MSW: | | MTHE: | | MTHR: | | MHOR: | | MBU: | | MMET: | | MMH: | | MHAZ: | | MEV: | | MZH: | | MPY: | | MHZ: | | MTP: | | MCJ: | | MHI: | | MHU: | | MLA: | | MEM: | | MBG: | | MEMA: | | MPI: | | MBN: | | MFO: | | MPL: | | MPD: | | MEZ: | | RCI: | | MTH: | | MMG: | | METC: | | MWO: | | MST: | | MSI: | | MRU: | | MEB: | | MMIL: | | MEYE: | | MOL: | | MEL: | | MEW: | | METH: | | MFC: | | MFI: | | MCUB: | | MFV: | | APO: | | AVE: | | FPL: | | GAC: | | GAH: | | HAL: | | HSL: | | HDL: | | HHB: | | HJE: | | HALH: | | HHSR: | | HSU: | | HSF: | | HMA: | | HHI: | | HHN: | | HAB: | | NPH: | | NMO: | | HUT: | | HTI: | | HMU: | | HALI: | | HWA: | | HWC: | | HVO: | | HME: | | HGI: | | HBO: | | HLA: | | HSI: | | HTU: | | HDA: | | NMG: | | HXA: | | NAT: | | NPE: | | NGE: | | HRU: | | NOU: | | SALI: | | HLR: | | HLC: | | NAJ: | | TAC: | | TVO: | | PTO: | | FAC: | | FAI: | | CDIV: | | TAR: | | MAX: | | MER: | | MEAR: | | MARC: | | PHO: | | PAB: | | PFU: | | PFI: | | PYN: | | PYA: | | PYS: | | TKO: | | TON: | | TGA: | | TSI: | | TBA: | | THE: | | THA: | | THM: | | TLT: | | THS: | | TNU: | | TEU: | | TGY: | | THV: | | TCH: | | TPEP: | | TPIE: | | PPAC: | | ABI: | | ACF: | | APE: | | ACJ: | | SMR: | | SHC: | | IHO: | | IIS: | | DKA: | | DFD: | | TAG: | | IAG: | | THG: | | HBU: | | PFM: | | PDL: | | SSO: | | SOL: | | SSOA: | | SSOL: | | SSOF: | | STO: | | SAI: | | SACN: | | SACR: | | SACS: | | SIS: | | SIA: | | SIM: | | SID: | | SIY: | | SIN: | | SII: | | SIH: | | SIR: | | SIC: | | SULA: | | MSE: | | MCN: | | AHO: | | AMAN: | | PAI: | | PIS: | | PCL: | | PAS: | | PYR: | | POG: | | TNE: | | PYW: | | CMA: | | TUZ: | | TTN: | | VDI: | | VMO: | | TPE: | | THB: | | TCB: | | THF: | | ASC: | | FFO: | | NMR: | | NIR: | | NID: | | NIN: | | NKR: | | NCT: | | CSY: | | NGA: | | NVN: | | NEV: | | TAA: | | CSU: | | NBV: | | TAH: | | NDV: | | NEQ: | | NAA: | | NAC: | | MARH: | | KCR: | | BARC: | | BARB: | | LOKI: | | HAH: | | AGW: | | ARG: | |
» show all
 |
|---|
| Reference |
|
|---|
| Authors |
Friedberg EC, Goldthwait DA. |
|---|
| Title |
Endonuclease II of E. coli. I. Isolation and purification. |
|---|
| Journal |
Proc. Natl. Acad. Sci. U. S. A. 62 (1969) 934-40. |
|---|
| Reference |
|
|---|
| Authors |
Friedberg EC, Hadi SM, Goldthwait DA. |
|---|
| Title |
Endonuclease II of Escherichia coli. II. Enzyme properties and studies on the degradation of alkylated and native deoxyribonucleic acid. |
|---|
| Journal |
J. Biol. Chem. 244 (1969) 5879-89. |
|---|
| Reference |
|
|---|
| Authors |
Hadi SM, Goldthwait DA. |
|---|
| Title |
Endonuclease II of Escherichia coli. Degradation of partially depurinated deoxyribonucleic acid. |
|---|
| Journal |
Biochemistry. 10 (1971) 4986-93. |
|---|
| Reference |
|
|---|
| Authors |
Cunningham RP, Saporito SM, Spitzer SG, Weiss B |
|---|
| Title |
Endonuclease IV (nfo) mutant of Escherichia coli. |
|---|
| Journal |
J. Bacteriol. 168 (1986) 1120-7. |
|---|
| Reference |
|
|---|
| Authors |
Ide H, Tedzuka K, Shimzu H, Kimura Y, Purmal AA, Wallace SS, Kow YW |
|---|
| Title |
Alpha-deoxyadenosine, a major anoxic radiolysis product of adenine in DNA, is a substrate for Escherichia coli endonuclease IV. |
|---|
| Journal |
Biochemistry. 33 (1994) 7842-7. |
|---|
| Reference |
|
|---|
| Authors |
Hosfield DJ, Guan Y, Haas BJ, Cunningham RP, Tainer JA |
|---|
| Title |
Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis. |
|---|
| Journal |
Cell. 98 (1999) 397-408. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 63363-78-0 |
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