KEGG   ENZYME: 3.1.22.1Help
Entry
EC 3.1.22.1                 Enzyme                                 

Name
deoxyribonuclease II;
DNase II;
pancreatic DNase II;
deoxyribonucleate 3'-nucleotidohydrolase;
DNase II;
pancreatic DNase II;
acid deoxyribonuclease;
acid DNase
Class
Hydrolases;
Acting on ester bonds;
Endodeoxyribonucleases producing 3'-phosphomonoesters
BRITE hierarchy
Reaction(IUBMB)
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products
Comment
Preference for double-stranded DNA.
History
EC 3.1.22.1 created 1961 as EC 3.1.4.6, transferred 1978 to EC 3.1.22.1, modified 1981
Orthology
K01158  
deoxyribonuclease II
Genes
HSA: 
1777(DNASE2) 58511(DNASE2B)
PTR: 
469369(DNASE2B) 747576(DNASE2)
PPS: 
100971929(DNASE2B) 100983965(DNASE2)
GGO: 
101138006(DNASE2B) 101145943(DNASE2)
PON: 
100171654(DNASE2) 100453264(DNASE2B)
NLE: 
100586795(DNASE2B) 100599185(DNASE2)
MCC: 
710197(DNASE2B) 716802(DNASE2)
MCF: 
102116438(DNASE2B) 102117817(DNASE2)
RRO: 
104661085(DNASE2) 104677492(DNASE2B)
CJC: 
100388793(DNASE2) 100409153(DNASE2B)
MMU: 
13423(Dnase2a) 56629(Dnase2b)
RNO: 
171575(Dnase2) 59296(Dnase2b)
CGE: 
100763100(Dnase2) 100767962(Dnase2b)
NGI: 
103728126(Dnase2b) 103751880(Dnase2)
HGL: 
101716162(Dnase2) 101719320(Dnase2b)
OCU: 
100343632(DNASE2) 100358625(DNASE2B)
TUP: 
102489174(DNASE2) 102500832(DNASE2B)
CFA: 
476697(DNASE2) 479973(DNASE2B)
AML: 
100470385(DNASE2B) 100478733(DNASE2)
UMR: 
103663110(DNASE2B) 103682150(DNASE2)
FCA: 
101086631(DNASE2) 101097005(DNASE2B)
PTG: 
102955307(DNASE2) 102971388(DNASE2B)
BTA: 
282218(DNASE2) 525117(DNASE2B)
BOM: 
102267450(DNASE2B) 102274104(DNASE2)
PHD: 
102330003(DNASE2B) 102335097(DNASE2)
CHX: 
102180029(DNASE2) 102191199(DNASE2B)
OAS: 
101105493(DNASE2) 101110100(DNASE2B)
SSC: 
100620625(DNASE2B) 397398(DNASE2)
CFR: 
102504882(DNASE2B) 102515557(DNASE2)
BACU: 
103004369(DNASE2) 103010260(DNASE2B)
LVE: 
103068859(DNASE2) 103070741(DNASE2B)
ECB: 
100064895(DNASE2B) 100147278(DNASE2)
MYB: 
102242953(DNASE2B) 102244884(DNASE2)
MYD: 
102751727(DNASE2) 102752051(DNASE2B)
PALE: 
102878930(DNASE2B) 102880783(DNASE2)
MDO: 
100012881(DNASE2B) 100027525(DNASE2)
SHR: 
100917174(DNASE2B) 100927318(DNASE2)
OAA: 
100075769(DNASE2)
GGA: 
424540(DNASE2B)
MGP: 
100548401(DNASE2B)
CJO: 
107317541(DNASE2B)
APLA: 
101792648(DNASE2B)
TGU: 
100231880(DNASE2B)
GFR: 
102040552(DNASE2B)
FAB: 
107603307(DNASE2B)
PHI: 
102112417(DNASE2B)
CCW: 
104695301(DNASE2B)
FPG: 
101917930(DNASE2B)
FCH: 
102059822(DNASE2B)
CLV: 
102094785(DNASE2B)
AAM: 
106499687(DNASE2B)
ASN: 
AMJ: 
102569684(DNASE2) 102571694(DNASE2B)
PSS: 
102453737(DNASE2B)
CMY: 
102937104(DNASE2) 102943737(DNASE2B)
ACS: 
100552794(dnase2b)
PBI: 
103065325(DNASE2)
GJA: 
107112001(DNASE2) 107117303(DNASE2B)
XLA: 
446506(dnase2)
XTR: 
496759(dnase2b) 733868(dnase2)
DRE: 
100000399(dnase2) 562996(dnase2b)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
103173520(dnase2) 103174707(dnase2b)
BFO: 
SPU: 
SKO: 
DME: 
Dmel_CG7780(DNaseII)
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD19194(Dsim_GD19194)
DWI: 
DYA: 
Dyak_GE25505(dyak_GLEANR_9130) Dyak_GE29217
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
413489(DNaseII)
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
TCA: 
BMOR: 
PXY: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG10104(Cbr-crn-6) CBG16650(Cbr-tag-198)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
SMM: 
VCN: 
CSL: 
CVR: 
DDI: 
DDB_G0290577(dnase2)
DPP: 
DFA: 
DFA_07386(dnase2)
ACAN: 
TET: 
PTM: 
SPAR: 
TVA: 
BPM: 
BPL: 
BPD: 
BPSE: 
BPSM: 
BPSU: 
BPSD: 
BPZ: 
BPQ: 
BPK: 
BPSH: 
BPSA: 
BPSO: 
BUT: 
BTQ: 
BTJ: 
BTZ: 
BTD: 
BTV: 
BTHE: 
BTHM: 
BTHA: 
BTHL: 
BOK: 
BOC: 
BUL: 
BUD: 
CMI: 
CMS: 
CMC: 
CMH: 
ARH: 
SATK: 
 » show all
Taxonomy
Reference
1
  Authors
Bernardi, G.
  Title
Spleen acid deoxyribonuclease.
  Journal
In: Cantoni, G.L. and Davies, D.R. (Eds.), Procedures in Nucleic Acid Research, Procedures in Nucleic Acid Research, New York, 1966, p. 102-121.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9025-64-3

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