KEGG   ENZYME: 3.1.22.1Help
Entry
EC 3.1.22.1                 Enzyme                                 

Name
deoxyribonuclease II;
DNase II;
pancreatic DNase II;
deoxyribonucleate 3'-nucleotidohydrolase;
DNase II;
pancreatic DNase II;
acid deoxyribonuclease;
acid DNase
Class
Hydrolases;
Acting on ester bonds;
Endodeoxyribonucleases producing 3'-phosphomonoesters
BRITE hierarchy
Reaction(IUBMB)
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products
Comment
Preference for double-stranded DNA.
History
EC 3.1.22.1 created 1961 as EC 3.1.4.6, transferred 1978 to EC 3.1.22.1, modified 1981
Orthology
K01158  deoxyribonuclease II
Genes
HSA: 1777(DNASE2) 58511(DNASE2B)
PTR: 469369(DNASE2B) 747576(DNASE2)
PPS: 100971929(DNASE2B) 100983965(DNASE2)
GGO: 101138006(DNASE2B) 101145943(DNASE2)
PON: 100171654(DNASE2) 100453264(DNASE2B)
NLE: 100586795(DNASE2B) 100599185(DNASE2)
MCC: 710197(DNASE2B) 716802(DNASE2)
MCF: 102116438(DNASE2B) 102117817(DNASE2)
CSAB: 103224537(DNASE2B) 103234370(DNASE2)
RRO: 104661085(DNASE2) 104677492(DNASE2B)
RBB: 108527686(DNASE2B) 108544114(DNASE2)
CJC: 100388793(DNASE2) 100409153(DNASE2B)
SBQ: 101044247(DNASE2) 101046560(DNASE2B)
MMU: 13423(Dnase2a) 56629(Dnase2b)
RNO: 171575(Dnase2) 59296(Dnase2b)
CGE: 100763100(Dnase2) 100767962(Dnase2b)
NGI: 103728126(Dnase2b) 103751880(Dnase2)
HGL: 101716162(Dnase2) 101719320(Dnase2b)
CCAN: 109681258(Dnase2) 109688704(Dnase2b)
OCU: 100343632(DNASE2) 100358625(DNASE2B)
TUP: 102489174(DNASE2) 102500832(DNASE2B)
CFA: 476697(DNASE2) 479973(DNASE2B)
AML: 100470385(DNASE2B) 100478733(DNASE2)
UMR: 103663110(DNASE2B) 103682150(DNASE2)
ORO: 101365858(DNASE2B) 101372958(DNASE2)
FCA: 101086631(DNASE2) 101097005(DNASE2B)
PTG: 102955307(DNASE2) 102971388(DNASE2B)
AJU: 106973349(DNASE2B) 106985618(DNASE2)
BTA: 282218(DNASE2) 525117(DNASE2B)
BOM: 102267450(DNASE2B) 102274104(DNASE2)
BIU: 109556135(DNASE2B) 109561533(DNASE2)
PHD: 102330003(DNASE2B) 102335097(DNASE2)
CHX: 102180029(DNASE2) 102191199(DNASE2B)
OAS: 101105493(DNASE2) 101110100(DNASE2B)
SSC: 100620625(DNASE2B) 397398(DNASE2)
CFR: 102504882(DNASE2B) 102515557(DNASE2)
CDK: 105095039(DNASE2B) 105100754(DNASE2)
BACU: 103004369(DNASE2) 103010260(DNASE2B)
LVE: 103068859(DNASE2) 103070741(DNASE2B)
OOR: 101275963(DNASE2B) 101280767(DNASE2) 105748883
ECB: 100064895(DNASE2B) 100147278(DNASE2)
EPZ: 103540639(DNASE2) 103557287(DNASE2B)
EAI: 106824010(DNASE2B) 106844341(DNASE2)
MYB: 102242953(DNASE2B) 102244884(DNASE2)
MYD: 102751727(DNASE2) 102752051(DNASE2B)
HAI: 109385434(DNASE2B) 109394275(DNASE2)
RSS: 109436573(DNASE2B) 109454963(DNASE2)
PALE: 102878930(DNASE2B) 102880783(DNASE2)
LAV: 100657160(DNASE2) 100668172(DNASE2B)
MDO: 100012881(DNASE2B) 100027525(DNASE2)
SHR: 100917174(DNASE2B) 100927318(DNASE2)
OAA: 100075769(DNASE2)
GGA: 424540(DNASE2B)
MGP: 100548401(DNASE2B)
CJO: 107317541(DNASE2B)
APLA: 101792648(DNASE2B)
ACYG: 106034063(DNASE2B)
TGU: 100231880(DNASE2B)
GFR: 102040552(DNASE2B)
FAB: 107603307(DNASE2B)
PHI: 102112417(DNASE2B)
PMAJ: 107208238(DNASE2B)
CCW: 104695301(DNASE2B)
FPG: 101917930(DNASE2B)
FCH: 102059822(DNASE2B)
CLV: 102094785(DNASE2B)
EGZ: 104122907(DNASE2B)
AAM: 106499687(DNASE2B)
AMJ: 102569684(DNASE2) 102571694(DNASE2B)
PSS: 102453737(DNASE2B)
CMY: 102937104(DNASE2) 102943737(DNASE2B)
CPIC: 101933598(DNASE2) 101936999(DNASE2B)
ACS: 100552794(dnase2b)
PVT: 110078007(DNASE2) 110079740(DNASE2B)
PBI: 103065325(DNASE2)
GJA: 107112001(DNASE2) 107117303(DNASE2B)
XLA: 108715496(dnase2b.S) 446506(dnase2.L)
XTR: 496759(dnase2b) 733868(dnase2)
NPR: 108791376(DNASE2B) 108799819(DNASE2)
DRE: 100000399(dnase2) 562996(dnase2b)
SRX: 107726682(dnase2) 107742910(dnase2b) 107745346
IPU: 108256294 108270716(dnase2b)
AMEX: 103028211 103030372(dnase2b)
NCC: 104941343 104941344(dnase2b) 104964581(dnase2)
CSEM: 103388950(dnase2) 103392263(dnase2b)
HCQ: 109512201(dnase2) 109522037(dnase2b)
ELS: 105021861(dnase2)
SFM: 108923499(dnase2b) 108926763
CMK: 103173520(dnase2) 103174707(dnase2b)
SKO: 102807747
DME: Dmel_CG7780(DNaseII)
DSI: Dsimw501_GD19194(Dsim_GD19194)
MDE: 101890173
AAG: 5576264
AME: 413489(DNaseII)
BIM: 100742638
BTER: 100651072
SOC: 105198320
AEC: 105147236
ACEP: 105619618
PBAR: 105426743
CFO: 105249606
LHU: 105668384
PGC: 109858774
NVI: 100123791
TCA: 103312693
NVL: 108561966
BMOR: 101746575
PMAC: 106710810
PRAP: 110996932
API: 100161890
DNX: 107173444
ZNE: 110836613
CEL: CELE_C07B5.5(nuc-1) CELE_F09G8.2(crn-7) CELE_K04H4.6(crn-6)
CBR: CBG10104(Cbr-crn-6) CBG16650(Cbr-tag-198)
OBI: 106880775
HMG: 100214979
DDI: DDB_G0290577(dnase2)
DFA: DFA_07386(dnase2)
SPAR: SPRG_13129
BPS: BPSS1983
BPSE: BDL_5397
BPSM: BBQ_4145
BPSU: BBN_5451
BPSD: BBX_4563
BPK: BBK_4726
BPSH: DR55_5746
BPSA: BBU_4025
BPSO: X996_5549
BUT: X994_5109
BTQ: BTQ_3681
BTJ: BTJ_4714
BTZ: BTL_5501
BTD: BTI_5010
BTV: BTHA_4702
BTHE: BTN_5171
BTHM: BTRA_5440
BTHA: DR62_5301
BTHL: BG87_5513
BOK: DM82_6277
BOC: BG90_4391
BUL: BW21_4547
CMI: CMM_1896
CMS: CMS1334
CMC: CMN_01874
 » show all
Taxonomy
Reference
1
  Authors
Bernardi, G.
  Title
Spleen acid deoxyribonuclease.
  Journal
In: Cantoni, G.L. and Davies, D.R. (Eds.), Procedures in Nucleic Acid Research, Procedures in Nucleic Acid Research, New York, 1966, p. 102-121.
Other DBs
ExplorEnz - The Enzyme Database: 3.1.22.1
IUBMB Enzyme Nomenclature: 3.1.22.1
ExPASy - ENZYME nomenclature database: 3.1.22.1
BRENDA, the Enzyme Database: 3.1.22.1
CAS: 9025-64-3

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