| Entry |
|
| Name |
deoxyribonuclease X;
Escherichia coli endodeoxyribonuclease;
Escherichia coli endodeoxyribonuclease X
|
| Class |
Hydrolases;
Acting on ester bonds;
Endodeoxyribonucleases producing 3'-phosphomonoesters
 |
| Reaction(IUBMB) |
Endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes
|
| Comment |
Preference for supercoiled DNA; little activity on linear double-stranded DNA. Inhibited by single-stranded DNA, ATP and AMP.
|
| Reference |
1 |
| Authors |
Ghosh, S. and DasGupta, U. |
| Title |
Studies with endonuclease X: a new deoxyendonuclease of E. coli that preferentially cleaves supercoiled plasmid DNA. |
| Journal |
Curr. Trends Life Sci. 12 (1984) 79-88. |
| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 97002-82-9 |