KEGG   ENZYME: 3.1.3.24Help
Entry
EC 3.1.3.24                 Enzyme                                 

Name
sucrose-phosphate phosphatase;
sucrose 6-phosphate hydrolase;
sucrose-phosphate hydrolase;
sucrose-phosphate phosphohydrolase;
sucrose-6-phosphatase;
sucrose phosphatase;
sucrose-6-phosphate phosphatase;
SPP
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
sucrose-6F-phosphate phosphohydrolase
Reaction(IUBMB)
sucrose 6F-phosphate + H2O = sucrose + phosphate [RN:R00805 R06211]
Reaction(KEGG)
Substrate
sucrose 6F-phosphate [CPD:C02591];
H2O [CPD:C00001]
Product
sucrose [CPD:C00089];
phosphate [CPD:C00009]
Comment
Requires Mg2+ for maximal activity [2]. This is the final step in the sucrose-biosynthesis pathway. The enzyme is highly specific for sucrose 6-phosphate, with fructose 6-phosphate unable to act as a substrate [2]. Belongs in the haloacid dehydrogenase (HAD) superfamily. The F of sucrose 6F-phosphate is used to indicate that the fructose residue of sucrose carries the substituent.
History
EC 3.1.3.24 created 1972, modified 2008
Pathway
Starch and sucrose metabolism
Metabolic pathways
Orthology
K07024  
sucrose-6-phosphatase 
Genes
ATH: 
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
VAR: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj0g3v0007959.1(Lj0g3v0007959.1) Lj0g3v0007959.2(Lj0g3v0007959.2) Lj0g3v0259839.1(Lj0g3v0259839.1) Lj0g3v0259849.1(Lj0g3v0259849.1) Lj6g3v0145980.1(Lj6g3v0145980.1) Lj6g3v0156190.1(Lj6g3v0156190.1) Lj6g3v0156190.2(Lj6g3v0156190.2) Lj6g3v0156190.3(Lj6g3v0156190.3)
LANG: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
POPTR_0006s21420g(POPTRDRAFT_561178) POPTR_0008s01390g(POPTRDRAFT_803094) POPTR_0016s06640g(POPTRDRAFT_576458)
VVI: 
SLY: 
SPEN: 
SOT: 
102577786(SPP2)
INI: 
SIND: 
BVG: 
NNU: 
OSA: 
4325448(OsJ_001789) 4328274(OsJ_005195) 4337789
DOSA: 
Os01t0376700-01(Os01g0376700) Os02t0143100-01(Os02g0143100) Os05t0144900-01(Os05g0144900)
OBR: 
BDI: 
ATS: 
SBI: 
SORBI_04g020180(SORBIDRAFT_04g020180) SORBI_09g003460(SORBIDRAFT_09g003460) SORBI_09g003463(SORBIDRAFT_09g003463)
ZMA: 
541868(spp1) 542661(GRMZM2G097641)
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
CSL: 
CVR: 
APRO: 
GTT: 
SSIL: 
PLN: 
PRT: 
PLL: 
PANA: 
PHC: 
SYN: 
SYZ: 
SYY: 
SYNGTS_1845(slr0953)
SYT: 
SYNGTI_1845(slr0953)
SYS: 
SYNPCCN_1844(slr0953)
SYQ: 
SYNPCCP_1844(slr0953)
SYJ: 
DSL: 
CMP: 
LEN: 
LET: 
AMR: 
HAO: 
GLP: 
CYT: 
CYC: 
CYN: 
CYJ: 
MIC: 
GEI: 
OAC: 
ONI: 
MPRO: 
CEP: 
GVI: 
GLJ: 
ANA: 
NPU: 
NOS: 
NOP: 
NON: 
AVA: 
ANB: 
ACY: 
AWA: 
NAZ: 
CSG: 
CALO: 
CALT: 
CALH: 
RIV: 
FIS: 
CTHE: 
PLP: 
SCS: 
 » show all
Taxonomy
Reference
1  [PMID:4290548]
  Authors
Hawker JS, Hatch MD.
  Title
A specific sucrose phosphatase from plant tissues.
  Journal
Biochem. J. 99 (1966) 102-7.
Reference
2  [PMID:11050182]
  Authors
Lunn JE, Ashton AR, Hatch MD, Heldt HW
  Title
Purification, molecular cloning, and sequence analysis of sucrose-6F-phosphate phosphohydrolase from plants.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 12914-9.
  Sequence
[zma:541868] [osa:4328274] [ath:AT2G35840 AT3G54270]
Reference
3  [PMID:12753969]
  Authors
Lunn JE, MacRae E
  Title
New complexities in the synthesis of sucrose.
  Journal
Curr. Opin. Plant. Biol. 6 (2003) 208-14.
Reference
4  [PMID:15937230]
  Authors
Fieulaine S, Lunn JE, Borel F, Ferrer JL
  Title
The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell.
  Journal
Plant. Cell. 17 (2005) 2049-58.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9059-33-0

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