KEGG   ENZYME: 3.1.3.31Help
Entry
EC 3.1.3.31                 Enzyme                                 

Name
nucleotidase;
nucleotide phosphatase;
nucleotide-specific phosphatase;
NSP I;
NSP II;
deoxyribonucleoside-activated nucleotidase (DAN);
deoxyinosine-activated nucleotidase (DIAN);
acid nucleotidase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
nucleotide phosphohydrolase
Reaction(IUBMB)
a nucleotide + H2O = a nucleoside + phosphate [RN:R01572]
Reaction(KEGG)
Substrate
nucleotide [CPD:C00215];
H2O [CPD:C00001]
Product
nucleoside [CPD:C00801];
phosphate [CPD:C00009]
Comment
A wide specificity for 2', 3'- and 5'- nucleotides; also hydrolyses glycerol phosphate and 4-nitrophenyl phosphate.
History
EC 3.1.3.31 created 1972 (EC 3.1.3.30 created 1972, incorporated 1992)
Reference
1  [PMID:5699060]
  Authors
Arsenis C, Touster O.
  Title
Purification and properties of an acid nucleotidase from rat liver lysosomes.
  Journal
J. Biol. Chem. 243 (1968) 5702-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9033-33-4

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