KEGG   ENZYME: 3.1.3.33Help
Entry
EC 3.1.3.33                 Enzyme                                 

Name
polynucleotide 5'-phosphatase;
5'-polynucleotidase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
polynucleotide 5'-phosphohydrolase
Reaction(IUBMB)
a 5'-phosphopolynucleotide + H2O = a polynucleotide + phosphate [RN:R02249]
Reaction(KEGG)
Substrate
5'-phosphopolynucleotide [CPD:C03475];
H2O [CPD:C00001]
Product
polynucleotide [CPD:C00419];
phosphate [CPD:C00009]
Comment
Does not act on nucleoside monophosphates. Induced in Escherichia coli by T-even phages.
History
EC 3.1.3.33 created 1972
Reference
1  [PMID:4289819]
  Authors
Becker A, Hurwitz J.
  Title
The enzymatic cleavage of phosphate termini from polynucleotides.
  Journal
J. Biol. Chem. 242 (1967) 936-50.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37288-17-8

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