KEGG   ENZYME: 3.1.3.35Help
Entry
EC 3.1.3.35                 Enzyme                                 

Name
thymidylate 5'-phosphatase;
thymidylate 5'-nucleotidase;
deoxythymidylate 5'-nucleotidase;
thymidylate nucleotidase;
deoxythymidylic 5'-nucleotidase;
deoxythymidylate phosphohydrolase;
dTMPase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
thymidylate 5'-phosphohydrolase
Reaction(IUBMB)
thymidylate + H2O = thymidine + phosphate [RN:R01569]
Reaction(KEGG)
Substrate
thymidylate [CPD:C00364];
H2O [CPD:C00001]
Product
thymidine [CPD:C00214];
phosphate [CPD:C00009]
Comment
Acts on 5-methyl-dCMP and on TMP, but more slowly than on dTMP.
History
EC 3.1.3.35 created 1972
Reference
1  [PMID:4958986]
  Authors
Aposhian HV, Tremblay GY.
  Title
Deoxythymidylate 5'-nucleotidase. Purification and properties of an enzyme found after infection of Bacillus subtilis with phage SP5C.
  Journal
J. Biol. Chem. 241 (1966) 5095-101.
  Organism
Bacillus subtilis
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9026-80-6

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