KEGG   ENZYME: 3.1.3.39Help
Entry
EC 3.1.3.39                 Enzyme                                 

Name
streptomycin-6-phosphatase;
streptomycin 6-phosphate phosphatase;
streptomycin 6-phosphate phosphohydrolase;
streptomycin-6-P phosphohydrolase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
streptomycin-6-phosphate phosphohydrolase
Reaction(IUBMB)
streptomycin 6-phosphate + H2O = streptomycin + phosphate [RN:R02228]
Reaction(KEGG)
Substrate
streptomycin 6-phosphate [CPD:C01138];
H2O [CPD:C00001]
Product
streptomycin [CPD:C00413];
phosphate [CPD:C00009]
Comment
Also acts on dihydrostreptomycin 3'alpha,6-bisphosphate and streptidine 6-phosphate.
History
EC 3.1.3.39 created 1976
Pathway
Streptomycin biosynthesis
Biosynthesis of secondary metabolites
Orthology
K04342  
streptomycin-6-phosphatase
Genes
SGR: 
SGR_5938(strK)
SCT: 
SCAT_5710(strK)
SCY: 
SBH: 
SRC: 
Taxonomy
Reference
1  [PMID:4121457]
  Authors
Walker JB, Skorvaga M.
  Title
Streptomycin biosynthesis and metabolism. Phosphate transfer from dihydrostreptomycin 6-phosphate to inosamines, streptamine, and 2-deoxystreptamine.
  Journal
J. Biol. Chem. 248 (1973) 2441-6.
Reference
2  [PMID:4331203]
  Authors
Walker MS, Walker JB.
  Title
Streptomycin biosynthesis. Separation and substrate specificities of phosphatases acting on guanidinodeoxy-scyllo-inositol phosphate and streptomycin-(streptidino)phosphate.
  Journal
J. Biol. Chem. 246 (1971) 7034-40.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9055-33-8

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