KEGG   ENZYME: 3.1.3.47Help
Entry
EC 3.1.3.47                 Enzyme                                 

Name
[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase;
reductase phosphatase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphate phosphohydrolase
Reaction(IUBMB)
[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O = [hydroxymethylglutaryl-CoA reductase (NADPH)] + phosphate [RN:R04542]
Reaction(KEGG)
Substrate
[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate [CPD:C04768];
H2O [CPD:C00001]
Product
[hydroxymethylglutaryl-CoA reductase (NADPH)] [CPD:C04632];
phosphate [CPD:C00009]
Comment
Acts on the product of the reaction catalysed by EC 2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase, simultaneously dephosphorylating and activating EC 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH).
History
EC 3.1.3.47 created 1984
Reference
1  [PMID:6282220]
  Authors
Gil G, Hegardt FG.
  Title
Some properties of purified 3-hydroxy-3-methylglutaryl coenzyme A reductase phosphatases from rat liver.
  Journal
Arch. Biochem. Biophys. 214 (1982) 192-8.
Reference
2  [PMID:6260210]
  Authors
Gil G, Sitges M, Hegardt FG.
  Title
Purification and properties of rat liver hydroxymethylglutaryl coenzyme A reductase phosphatases.
  Journal
Biochim. Biophys. Acta. 663 (1981) 211-21.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
73507-97-8

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