KEGG   ENZYME: 3.1.3.84Help
Entry
EC 3.1.3.84                 Enzyme                                 

Name
ADP-ribose 1''-phosphate phosphatase;
POA1;
Appr1p phosphatase;
Poa1p;
ADP-ribose 1''-phosphate phosphohydrolase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
ADP-D-ribose 1''-phosphate phosphohydrolase
Reaction(IUBMB)
ADP-D-ribose 1''-phosphate + H2O = ADP-D-ribose + phosphate
Substrate
ADP-D-ribose 1''-phosphate;
H2O [CPD:C00001]
Product
ADP-D-ribose [CPD:C00301];
phosphate [CPD:C00009]
Comment
The enzyme is highly specific for ADP-D-ribose 1''-phosphate. Involved together with EC 3.1.4.37, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, in the breakdown of adenosine diphosphate ribose 1'',2''-cyclic phosphate (Appr>p), a by-product of tRNA splicing.
History
EC 3.1.3.84 created 2011
Orthology
K15529  
ADP-ribose 1''-phosphate phosphatase
Genes
SCE: 
YBR022W(POA1)
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0A10220(NCAS0A10220)
NDI: 
NDAI_0A07250(NDAI0A07250)
TPF: 
TPHA_0A04210(TPHA0A04210)
TBL: 
TBLA_0I01770(TBLA0I01770)
KAF: 
KAFR_0F02400(KAFR0F02400)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CTP: 
COT: 
CDU: 
YLI: 
CLU: 
TTT: 
MTM: 
CTHR: 
TMN: 
FGR: 
FPU: 
NHE: 
CMT: 
AFM: 
AOR: 
AOR_1_1836174(AO090005001055)
ANG: 
AFV: 
ACT: 
NFI: 
CIM: 
CPW: 
PBL: 
PBN: 
URE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
ADL: 
 » show all
Taxonomy
Reference
1  [PMID:15684411]
  Authors
Shull NP, Spinelli SL, Phizicky EM
  Title
A highly specific phosphatase that acts on ADP-ribose 1''-phosphate, a metabolite of tRNA splicing in Saccharomyces cerevisiae.
  Journal
Nucleic. Acids. Res. 33 (2005) 650-60.
  Sequence
[sce:YBR022W]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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