KEGG   ENZYME: 3.1.3.87Help
Entry
EC 3.1.3.87                 Enzyme                                 

Name
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase;
HK-MTPenyl-1-P phosphatase;
MtnX;
YkrX
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate phosphohydrolase
Reaction(IUBMB)
2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate [RN:R07394]
Reaction(KEGG)
Substrate
2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate [CPD:C15651];
H2O [CPD:C00001]
Product
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one [CPD:C15606];
phosphate [CPD:C00009]
Comment
The enzyme participates in the methionine salvage pathway in Bacillus subtilis [2].
In some species a single bifunctional enzyme, EC 3.1.3.77, acireductone synthase, catalyses both this reaction and EC 5.3.2.5, 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [1].
History
EC 3.1.3.87 created 2012
Pathway
Cysteine and methionine metabolism
Metabolic pathways
Orthology
K08966  
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
Genes
DAL: 
ADE: 
ACP: 
AFW: 
ANK: 
SCL: 
AFE: 
AFR: 
ACU: 
ACZ: 
AFI: 
BSU: 
BSU13600(mtnX)
BSR: 
I33_1531(mtnX)
BSL: 
BSH: 
BSY: 
BSUT: 
BSUL: 
BSUS: 
BSS: 
BST: 
GYO_1687(mtnX)
BSO: 
BSN: 
BSQ: 
BSX: 
C663_1401(mtnX)
BLI: 
BL03541(mtnB)
BLD: 
BLi01516(mtnB_mtnX)
BLH: 
BAY: 
BAQ: 
BYA: 
BAMP: 
BAML: 
BAMA: 
RBAU_1316(mtnX)
BAMN: 
BASU_1295(mtnX)
BAMB: 
BAMT: 
BAMY: 
BMP: 
BAZ: 
BQL: 
LL3_01462(mtnX)
BXH: 
BQY: 
MUS_1441(mtnX)
BAMI: 
BAMC: 
BAMF: 
BAE: 
BATR: 
BAN: 
BA_4256(mtnX)
BAR: 
GBAA_4256(mtnX)
BAT: 
BAS3947(mtnX)
BAH: 
BAI: 
BAA_4279(mtnX)
BAX: 
BANT: 
BANR: 
BANS: 
BANH: 
BANV: 
DJ46_2948(mtnX)
BAL: 
BCE: 
BC4037(mtnX)
BCA: 
BCZ: 
BCR: 
BCB: 
BCU: 
BCG: 
BCQ: 
BCX: 
BCA_4150(mtnX)
BNC: 
BCF: 
BCER: 
BCK_15015(mtnX)
BCEF: 
BCY: 
BTK: 
BTL: 
BTB: 
BTT: 
BTHR: 
BTHI: 
BTK_21345(mtnX)
BTC: 
BTF: 
BTM: 
MC28_3329(mtnX)
BTG: 
BTI: 
BTG_29235(mtnX)
BTN: 
BTHT: 
BTHU: 
BTW: 
BF38_5210(mtnX)
BWE: 
BWW: 
bwei_0914(mtnX)
BTY: 
BMYC: 
DJ92_1132(mtnX)
BMYO: 
BG05_1985(mtnX)
BPU: 
BPUM_1253(mtnX)
BPUM: 
BPF: 
BMQ: 
BMQ_1251(mtnX)
BMD: 
BMD_1235(mtnX)
BMH: 
BMEG: 
BG04_3550(mtnX)
BJS: 
BIF: 
BLE: 
BMET: 
GST: 
BACW: 
BACP: 
BACB: 
BBY: 
BACY: 
BACL: 
BALM: 
BEO: 
BEH_04820(mtnX)
BSM: 
BSJ: 
GKA: 
GTN: 
GTH: 
GTE: 
GWC: 
GYC: 
GYA: 
GCT: 
GMC: 
GGH: 
GJF: 
GEA: 
GEL: 
GSE: 
AFL: 
AGN: 
LSP: 
LGY: 
LFU: 
FPN: 
ESI: 
EAT: 
EAN: 
Eab7_0404(mtnX)
EXM: 
BBE: 
BLR: 
PJD: 
GYM: 
PPY: 
PPE_02690(mtnX)
PPM: 
PPO: 
PPM_2882(ykrX)
PPOL: 
PPQ: 
PPOY: 
PMS: 
PMQ: 
PMW: 
B2K_27875(mtnX)
PTA: 
PLV: 
PBJ: 
PIH: 
PPEO: 
PNP: 
POW: 
TCO: 
ANX: 
AAC: 
AAD: 
TC41_0119(mtnX)
JEO: 
SAY: 
TPY_2540(mtnX)
SAP: 
NTH: 
SYC: 
SYF: 
SYR: 
SYU: 
MAR: 
MPK: 
CYP: 
CYC: 
CYH: 
CYJ: 
DSL: 
HAO: 
LEP: 
LEN: 
GEI: 
OAC: 
ONI: 
MIC: 
ARP: 
NON: 
CSG: 
CALO: 
CALT: 
CALH: 
RIV: 
PLP: 
SCS: 
FIS: 
DEV: 
DEG: 
DMC: 
DMD: 
DMG: 
DMX: 
DMZ: 
DUC: 
DLY: 
DEW: 
TTR: 
PMX: 
LFC: 
LFI: 
LFP: 
LEG: 
MOX: 
 » show all
Taxonomy
Reference
1  [PMID:8227039]
  Authors
Myers RW, Wray JW, Fish S, Abeles RH.
  Title
Purification and characterization of an enzyme involved in oxidative carbon-carbon bond cleavage reactions in the methionine salvage pathway of Klebsiella pneumoniae.
  Journal
J. Biol. Chem. 268 (1993) 24785-91.
Reference
2  [PMID:14551435]
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science. 302 (2003) 286-90.
  Sequence
[bsu:BSU13600]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

DBGET integrated database retrieval system