KEGG   ENZYME: 3.1.4.2Help
Entry
EC 3.1.4.2                  Enzyme                                 

Name
glycerophosphocholine phosphodiesterase;
glycerophosphinicocholine diesterase;
glycerylphosphorylcholinediesterase;
sn-glycero-3-phosphorylcholine diesterase;
glycerolphosphorylcholine phosphodiesterase;
glycerophosphohydrolase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-diester hydrolases
BRITE hierarchy
Sysname
sn-glycero-3-phosphocholine glycerophosphohydrolase
Reaction(IUBMB)
sn-glycero-3-phosphocholine + H2O = choline + sn-glycerol 3-phosphate [RN:R01030]
Reaction(KEGG)
R01030;
(other) R01470
Show
Substrate
sn-glycero-3-phosphocholine [CPD:C00670];
H2O [CPD:C00001]
Product
choline [CPD:C00114];
sn-glycerol 3-phosphate [CPD:C00093]
Comment
Also acts on sn-glycero-3-phosphoethanolamine.
History
EC 3.1.4.2 created 1961, modified 1976
Pathway
Glycerophospholipid metabolism
Orthology
K18695  
glycerophosphocholine phosphodiesterase GPCPD1
Genes
HSA: 
56261(GPCPD1)
PTR: 
458085(GPCPD1)
PPS: 
100992325(GPCPD1)
GGO: 
101144579(GPCPD1)
PON: 
100457313(GPCPD1)
NLE: 
100585965(GPCPD1)
MCC: 
719117(GPCPD1)
MCF: 
102119326(GPCPD1)
RRO: 
104674573(GPCPD1)
CJC: 
100403898(GPCPD1)
MMU: 
74182(Gpcpd1)
RNO: 
362219(Gpcpd1)
CGE: 
100772527(Gpcpd1)
NGI: 
HGL: 
101716686(Gpcpd1)
OCU: 
100340388(GPCPD1)
TUP: 
102476992(GPCPD1)
CFA: 
485778(GPCPD1)
AML: 
100464203(GPCPD1)
UMR: 
103674412(GPCPD1)
FCA: 
101081213(GPCPD1)
PTG: 
102966968(GPCPD1)
BTA: 
518469(GPCPD1)
BOM: 
102271682(GPCPD1)
PHD: 
102323961(GPCPD1)
CHX: 
102172822(GPCPD1)
OAS: 
101115143(GPCPD1)
SSC: 
100152321(GPCPD1)
CFR: 
102516881(GPCPD1)
BACU: 
103000701(GPCPD1)
LVE: 
103090265(GPCPD1)
ECB: 
100051946(GPCPD1)
MYB: 
102244847(GPCPD1)
MYD: 
PALE: 
102889103(GPCPD1)
MDO: 
100033295(GPCPD1)
SHR: 
100923561(GPCPD1)
OAA: 
100083805(GPCPD1)
GGA: 
421311(GPCPD1)
MGP: 
100543090(GPCPD1)
CJO: 
107310902(GPCPD1)
APLA: 
101795969(GPCPD1)
TGU: 
GFR: 
102037405(GPCPD1)
FAB: 
101809898(GPCPD1)
PHI: 
102106750(GPCPD1)
CCW: 
104696625(GPCPD1)
FPG: 
101911738(GPCPD1)
FCH: 
102047465(GPCPD1)
CLV: 
102085356(GPCPD1)
AAM: 
106499795(GPCPD1)
ASN: 
102375902(GPCPD1)
AMJ: 
102563733(GPCPD1)
PSS: 
102452347(GPCPD1)
CMY: 
102937446(GPCPD1)
ACS: 
100554925(gpcpd1)
PBI: 
103049142(GPCPD1)
GJA: 
107107082(GPCPD1)
XLA: 
735213(gpcpd1)
XTR: 
100216176(gpcpd1)
DRE: 
492483(gpcpd1)
TRU: 
101064928(gpcpd1)
MZE: 
101468338(gpcpd1)
OLA: 
101160778(gpcpd1)
XMA: 
102224753(gpcpd1)
LCM: 
102367204(GPCPD1)
CMK: 
103181646(gpcpd1)
BFO: 
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD23248(Dsim_GD23248)
DWI: 
DYA: 
Dyak_GE18251(dyak_GLEANR_2044) Dyak_GE22792(dyak_GLEANR_6546)
DGR: 
DMO: 
DVI: 
MDE: 
AAG: 
CQU: 
AME: 
410117(GB13115)
SOC: 
AEC: 
HST: 
CFO: 
TCA: 
PXY: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
BMY: 
LOA: 
TSP: 
LGI: 
CRG: 
OBI: 
SMM: 
 » show all
Taxonomy
Reference
1  [PMID:13315235]
  Authors
DAWSON RM.
  Title
Liver glycerylphosphorylcholine diesterase.
  Journal
Biochem. J. 62 (1956) 689-93.
Reference
2  [PMID:13143024]
  Authors
HAYAISHI O, KORNBERG A.
  Title
Metabolism of phospholipides by bacterial enzymes.
  Journal
J. Biol. Chem. 206 (1954) 647-63.
Reference
3  [PMID:13403918]
  Authors
WEBSTER GR, MARPLES EA, THOMPSON RH.
  Title
Glycerylphosphorylcholine diesterase activity of nervous tissue.
  Journal
Biochem. J. 65 (1957) 374-7.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9025-85-8

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