| Entry |
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| Name |
N-acetylgalactosamine-4-sulfatase;
chondroitinsulfatase;
chondroitinase;
arylsulfatase B;
acetylgalactosamine 4-sulfatase;
N-acetylgalactosamine 4-sulfate sulfohydrolase
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| Class |
Hydrolases;
Acting on ester bonds;
Sulfuric-ester hydrolases
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| Sysname |
N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase
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| Reaction(IUBMB) |
Hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate [RN: R07823]
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| Reaction(KEGG) |
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| Comment |
Acts also on N-acetylglucosamine 4-sulfate.
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| History |
EC 3.1.6.12 created 1984
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| Pathway |
| Glycosaminoglycan degradation | | Metabolic pathways |
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| Orthology |
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| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | NLE: | | MCC: | | MCF: | | CSAB: | | RRO: | | CJC: | | SBQ: | | MMU: | | RNO: | | CGE: | | NGI: | | HGL: | | CCAN: | | OCU: | | TUP: | | CFA: | | AML: | | UMR: | | FCA: | | PTG: | | AJU: | | BTA: | | BOM: | | BIU: | | PHD: | | CHX: | | OAS: | | SSC: | | CFR: | | BACU: | | LVE: | | ECB: | | MYB: | | MYD: | | HAI: | | PALE: | | LAV: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | CJO: | | APLA: | | TGU: | | GFR: | | FAB: | | PHI: | | CCW: | | FPG: | | FCH: | | CLV: | | AAM: | | ASN: | | AMJ: | | PSS: | | CMY: | | CPIC: | | ACS: | | PBI: | | GJA: | | XLA: | | XTR: | | DRE: | | IPU: | | TRU: | | LCO: | | MZE: | | OLA: | | XMA: | | SASA: | | LCM: | | CMK: | | BFO: | | CIN: | | SPU: | | SKO: | | DME: | | CRG: | | OBI: | | PTI: | | EHX: | | RBA: | |
» show all
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| Reference |
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| Authors |
Farooqui AA. |
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| Title |
The desulphation of hexosamine sulphates by arylsulphatase B. |
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| Journal |
Experientia. 32 (1976) 1242-4. |
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| Reference |
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| Authors |
Gorham SD, Cantz M. |
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| Title |
Arylsulphatase B, an exo-sulphatase for chondroitin 4-sulphate tetrasaccharide. |
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| Journal |
Hoppe. Seylers. Z. Physiol. Chem. 359 (1978) 1811-4. |
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| Reference |
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| Authors |
Tsuji M, Nakanishi Y, Habuchi H, Ishihara K, Suzuki S. |
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| Title |
The common identity of UDP-N-acetylgalactosamine 4-sulfatase, nitrocatechol sulfatase (arylsulfatase), and chondroitin 4-sulfatase. |
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| Journal |
Biochim. Biophys. Acta. 612 (1980) 373-83. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 55354-43-3 |
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