KEGG   ENZYME: 3.1.7.10Help
Entry
EC 3.1.7.10                 Enzyme                                 

Name
(13E)-labda-7,13-dien-15-ol synthase;
labda-7,13E-dien-15-ol synthase
Class
Hydrolases;
Acting on ester bonds;
Diphosphoric-monoester hydrolases
BRITE hierarchy
Sysname
geranylgeranyl-diphosphate diphosphohydrolase [(13E)-labda-7,13-dien-15-ol-forming]
Reaction(IUBMB)
geranylgeranyl diphosphate + H2O = (13E)-labda-7,13-dien-15-ol + diphosphate [RN:R09874]
Reaction(KEGG)
Substrate
geranylgeranyl diphosphate [CPD:C00353];
H2O [CPD:C00001]
Product
(13E)-labda-7,13-dien-15-ol [CPD:C20158];
diphosphate [CPD:C00013]
Comment
The enzyme from the lycophyte Selaginella moellendorffii is bifunctional, initially forming (13E)-labda-7,13-dien-15-yl diphosphate, which is hydrolysed to the alcohol.
History
EC 3.1.7.10 created 2012
Pathway
Diterpenoid biosynthesis
Biosynthesis of secondary metabolites
Orthology
K16086  
(13E)-labda-7,13-dien-15-ol synthase
Genes
SMO: 
Taxonomy
Reference
1  [PMID:21751328]
  Authors
Mafu S, Hillwig ML, Peters RJ
  Title
A novel labda-7,13e-dien-15-ol-producing bifunctional diterpene synthase from Selaginella moellendorffii.
  Journal
Chembiochem. 12 (2011) 1984-7.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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