KEGG   ENZYME: 3.10.1.1Help
Entry
EC 3.10.1.1                 Enzyme                                 

Name
N-sulfoglucosamine sulfohydrolase;
sulfoglucosamine sulfamidase;
heparin sulfamidase;
2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate sulphohydrolase)
Class
Hydrolases;
Acting on sulfur-nitrogen bonds;
Acting on sulfur-nitrogen bonds (only sub-subclass identified to date)
BRITE hierarchy
Sysname
N-sulfo-D-glucosamine sulfohydrolase
Reaction(IUBMB)
N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate [RN:R01963]
Reaction(KEGG)
R01963;
(other) R07814(G)
Show
Substrate
N-sulfo-D-glucosamine [CPD:C01075];
H2O [CPD:C00001]
Product
D-glucosamine [CPD:C00329];
sulfate [CPD:C00059]
History
EC 3.10.1.1 created 1972, modified 1981, modified 1982
Pathway
Glycosaminoglycan degradation
Metabolic pathways
Orthology
K01565  
N-sulfoglucosamine sulfohydrolase
Genes
HSA: 
6448(SGSH)
PTR: 
745502(SGSH)
PPS: 
100985307(SGSH)
GGO: 
101142618(SGSH)
PON: 
100459478(SGSH)
NLE: 
100588596(SGSH)
MCC: 
717977(SGSH)
MCF: 
102142565(SGSH)
CJC: 
100411890(SGSH)
MMU: 
27029(Sgsh)
RNO: 
688293(Sgsh)
CGE: 
100755391(Sgsh)
NGI: 
103730575(Sgsh)
HGL: 
101720611(Sgsh)
OCU: 
103347002(SGSH)
TUP: 
102473234(SGSH)
CFA: 
403707(SGSH)
AML: 
100477824(SGSH)
UMR: 
103665802(SGSH)
FCA: 
101094715(SGSH)
PTG: 
102957138(SGSH)
BTA: 
535442(SGSH)
BOM: 
102274142(SGSH)
PHD: 
102320007(SGSH)
CHX: 
102175240(SGSH)
OAS: 
101121184(SGSH)
SSC: 
100737146(SGSH)
CFR: 
102511664(SGSH)
BACU: 
102997141(SGSH)
LVE: 
103089895(SGSH)
ECB: 
100056499(SGSH)
MYB: 
102239046(SGSH)
MYD: 
102753251(SGSH)
PALE: 
102893583(SGSH)
MDO: 
100030803(SGSH)
SHR: 
100932279(SGSH)
OAA: 
100079215(SGSH)
GGA: 
422081(SGSH)
MGP: 
APLA: 
101802512(SGSH)
TGU: 
100230664(SGSH)
FAB: 
101812983(SGSH)
PHI: 
102110099(SGSH)
FPG: 
101918825(SGSH)
FCH: 
102050903(SGSH)
CLV: 
102090183(SGSH)
ASN: 
102382451(SGSH)
AMJ: 
102576386(SGSH)
PSS: 
102460593(SGSH)
CMY: 
102940151(SGSH)
ACS: 
100561423(sgsh)
PBI: 
103064462(SGSH)
XTR: 
100145064(sgsh)
DRE: 
563849(sgsh)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102349697(SGSH)
CMK: 
103175583(sgsh)
BFO: 
CIN: 
100183665(sgsh)
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
101887821(Sulfatase)
AGA: 
AAG: 
CQU: 
AME: 
550884(GB14747)
NVI: 
TCA: 
BMOR: 
PHU: 
ISC: 
LGI: 
NVE: 
AQU: 
TTT: 
TMN: 
FGR: 
NHE: 
ELA: 
ANG: 
ANI_1_1460064(An07g01010)
ZTR: 
PFJ: 
BCOM: 
DJI: 
GAG: 
PBS: 
IPA: 
CMR: 
EVI: 
ZGA: 
 » show all
Taxonomy
Reference
1  [PMID:5775690]
  Authors
Dietrich CP.
  Title
Enzymic degradation of heparin. A sulphamidase and a sulphoesterase from Flavobacterium heparinum.
  Journal
Biochem. J. 111 (1969) 91-5.
Reference
2  [PMID:6849981]
  Authors
Mahuran D, Clements P, Hopwood J.
  Title
A rapid four column purification of 2-deoxy-D-glucoside-2-sulphamate sulphohydrolase from human liver.
  Journal
Biochim. Biophys. Acta. 757 (1983) 359-65.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37289-41-1

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