KEGG   ENZYME: 3.10.1.2Help
Entry
EC 3.10.1.2                 Enzyme                                 

Name
cyclamate sulfohydrolase;
cyclamate sulfamatase;
cyclamate sulfamidase;
cyclohexylsulfamate sulfamidase
Class
Hydrolases;
Acting on sulfur-nitrogen bonds;
Acting on sulfur-nitrogen bonds (only sub-subclass identified to date)
BRITE hierarchy
Sysname
cyclohexylsulfamate sulfohydrolase
Reaction(IUBMB)
cyclohexylsulfamate + H2O = cyclohexylamine + sulfate [RN:R02564]
Reaction(KEGG)
Substrate
cyclohexylsulfamate [CPD:C02824];
H2O [CPD:C00001]
Product
cyclohexylamine [CPD:C00571];
sulfate [CPD:C00059]
Comment
Also readily hydrolyses aliphatic sulfamates with 3 to 8 carbons.
History
EC 3.10.1.2 created 1976, modified 1981
Pathway
Caprolactam degradation
Microbial metabolism in diverse environments
Reference
1  [PMID:4209783]
  Authors
Nimura T, Tokieda T, Yamaha T.
  Title
Partial purification and some properties of cyclamate sulfamatase.
  Journal
J. Biochem. (Tokyo). 75 (1974) 407-17.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
52228-00-9

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