| Entry |
|
|---|
| Name |
2'-hydroxybiphenyl-2-sulfinate desulfinase;
gene dszB-encoded hydrolase;
2-(2-hydroxyphenyl) benzenesulfinate:H2O hydrolase;
DszB;
HBPSi desulfinase;
2-(2-hydroxyphenyl) benzenesulfinate sulfohydrolase;
HPBS desulfinase;
2-(2-hydroxyphenyl)benzenesulfinate hydrolase;
2-(2'-hydroxyphenyl)benzenesulfinate desulfinase;
2-(2-hydroxyphenyl)benzenesulfinate desulfinase |
|---|
| Class |
Hydrolases;
Acting on carbon-sulfur bonds;
Acting on carbon-sulfur bonds (only sub-subclass identified to date)
 |
|---|
| Sysname |
2'-hydroxybiphenyl-2-sulfinate sulfohydrolase |
|---|
| Reaction(IUBMB) |
2'-hydroxybiphenyl-2-sulfinate + H2O = 2-hydroxybiphenyl + sulfite
[RN:R07311] |
|---|
| Reaction(KEGG) |
R07311
 |
|---|
| Substrate |
2'-hydroxybiphenyl-2-sulfinate [CPD:C06742];
H2O [CPD:C00001] |
|---|
| Product |
2-hydroxybiphenyl [CPD:C02499];
sulfite [CPD:C00094] |
|---|
| Comment |
The enzyme from Rhodococcus sp. strain IGTS8 is encoded by the
plasmid-encoded dibenzothiophene-desulfurization (dsz) operon. The
enzyme has a narrow substrate specificity with biphenyl-2-sulfinate
being the only other substrate known to date [2]. |
|---|
| Orthology |
KO: K05977 2'-hydroxybiphenyl-2-sulfinate desulfinase |
|---|
| Genes |
PEN: PSEEN3424 PSEEN3429
ACI: ACIAD1503 ACIAD1512
MAV: MAV_3808
RHA: RHA1_ro07049
 |
|---|
| Structures |
PDB: 2DE2 2DE3 2DE4 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:9308179]
Oldfield C, Pogrebinsky O, Simmonds J, Olson ES, Kulpa CF.
Elucidation of the metabolic pathway for dibenzothiophene
desulphurization by Rhodococcus sp. strain IGTS8 (ATCC 53968).
Microbiology. 143 ( Pt 9) (1997) 2961-73.
Rhodococcus erythropolis [GN:rer] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:12147352]
Nakayama N, Matsubara T, Ohshiro T, Moroto Y, Kawata Y, Koizumi K,
Hirakawa Y, Suzuki M, Maruhashi K, Izumi Y, Kurane R.
A novel enzyme, 2'-hydroxybiphenyl-2-sulfinate desulfinase (DszB),
from a dibenzothiophene-desulfurizing bacterium Rhodococcus
erythropolis KA2-5-1: gene overexpression and enzyme
characterization.
Biochim. Biophys. Acta. 1598 (2002) 122-30.
Rhodococcus erythropolis [GN:rer] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:12801508]
Watkins LM, Rodriguez R, Schneider D, Broderick R, Cruz M, Chambers
R, Ruckman E, Cody M, Mrachko GT.
Purification and characterization of the aromatic desulfinase,
2-(2'-hydroxyphenyl)benzenesulfinate desulfinase.
Arch. Biochem. Biophys. 415 (2003) 14-23.
Rhodococcus sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.13.1.3
IUBMB Enzyme Nomenclature: 3.13.1.3
ExPASy - ENZYME nomenclature database: 3.13.1.3
UM-BBD (Biocatalysis/Biodegradation Database): 3.13.1.3
BRENDA, the Enzyme Database: 3.13.1.3
CAS: 198154-06-2 |
|---|
