KEGG   ENZYME: 3.2.1.107Help
Entry
EC 3.2.1.107                Enzyme                                 

Name
protein-glucosylgalactosylhydroxylysine glucosidase;
2-O-alpha-D-glucopyranosyl-5-O-alpha-D-galactopyranosylhydroxy-L-lysine glucohydrolase;
protein-alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine glucohydrolase
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
protein-alpha-D-glucosyl-(1->2)-beta-D-galactosyl-L-hydroxylysine glucohydrolase
Reaction(IUBMB)
protein alpha-D-glucosyl-(1->2)-beta-D-galactosyl-L-hydroxylysine + H2O = D-glucose + protein beta-D-galactosyl-L-hydroxylysine [RN:R04503]
Reaction(KEGG)
Substrate
protein alpha-D-glucosyl-(1->2)-beta-D-galactosyl-L-hydroxylysine;
H2O [CPD:C00001]
Product
D-glucose [CPD:C00031];
protein beta-D-galactosyl-L-hydroxylysine [CPD:C04542]
Comment
Requires free, positively charged epsilon-amino group of hydroxylysine.
History
EC 3.2.1.107 created 1984
Reference
1  [PMID:385589]
  Authors
Hamazaki H, Hotta K.
  Title
Purification and characterization of an alpha-glucosidase specific for hydroxylysine-linked disaccharide of collagen.
  Journal
J. Biol. Chem. 254 (1979) 9682-7.
Reference
2  [PMID:7460918]
  Authors
Hamazaki H, Hotta K.
  Title
Enzymatic hydrolysis of disaccharide unit of collagen. Isolation of 2-O-alpha-D-glucopyranosyl-O-beta-D-galactopyranosyl-hydroxylysine glucohydrolase from rat spleens.
  Journal
Eur. J. Biochem. 111 (1980) 587-91.
Reference
3  [PMID:385599]
  Authors
Sternberg M, Spiro RG.
  Title
Studies on the catabolism of the hydroxylysine-linked disaccharide units of basement membranes and collagens. Isolation and characterization of a rat kidney alpha-glucosidase of high specificity.
  Journal
J. Biol. Chem. 254 (1979) 10329-36.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
72829-45-9

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