KEGG   ENZYME: 3.2.1.163Help
Entry
EC 3.2.1.163                Enzyme                                 

Name
1,6-alpha-D-mannosidase
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
(1->6)-alpha-mannosyl alpha-D-mannohydrolase
Reaction(IUBMB)
Hydrolysis of the (1->6)-linked alpha-D-mannose residues in alpha-D-Manp-(1->6)-D-Manp [RN:R10809]
Reaction(KEGG)
Comment
The enzyme is specific for (1->6)-linked mannobiose and has no activity towards any other linkages, or towards p-nitrophenyl-alpha-D-mannopyranoside or baker's yeast mannan. It is strongly inhibited by Mn2+ but does not require Ca2+ or any other metal cofactor for activity.
History
EC 3.2.1.163 created 2007
Reference
1  [PMID:15721331]
  Authors
Athanasopoulos VI, Niranjan K, Rastall RA.
  Title
The production, purification and characterisation of two novel alpha-D-mannosidases from Aspergillus phoenicis.
  Journal
Carbohydr. Res. 340 (2005) 609-17.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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