KEGG ENZYME: 3.2.1.205

ENZYME: 3.2.1.205

Entry

EC 3.2.1.205                Enzyme

Name

isomaltose glucohydrolase

Class

Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

Sysname

isomaltose 6-alpha-glucohydrolase (configuration-inverting)

Reaction(IUBMB)

isomaltose + H2O = beta-D-glucose + D-glucose [RN:R11791]

Reaction(KEGG)

R11791

Substrate

isomaltose [CPD:C00252];
H2O [CPD:C00001]

Product

beta-D-glucose [CPD:C00221];
D-glucose [CPD:C00031]

Comment

The enzyme catalyses the hydrolysis of alpha-1,6-glucosidic linkages from the non-reducing end of its substrate. Unlike EC 3.2.1.10, oligo-1,6-glucosidase, the enzyme inverts the anomeric configuration of the released residue. The enzyme can also act on panose and maltotriose at a lower rate.

History

EC 3.2.1.205 created 2017

Orthology

K22308

isomaltose glucohydrolase

Genes

LEIF:

HF024_18500

LSE:	F1C12_16080

MHOS:

CXR34_12440

MBIN:

LXM64_10375

CHRE:

IE160_08400

MHUM:

NNL39_09755

NAEI:

GCM126_24280

CELC:

K5O09_03050

CCHE:

NP064_12690

HALT:

IM660_06185

RHAL:

LQF10_13520

DEM:	LGT36_006965

NCA:

Noca_4631

NCQ:	K6T13_12790

KFL:

Kfla_1896

KQI:	F1D05_29275

KSL:	OG809_21355

NOA:	BKM31_21910

NGN:	LCN96_29625

NAKA:

H7F38_01830 H7F38_19775

DVC:	Dvina_30565

AYM:	YM304_31650

» show all

Reference

1 [PMID:27302067]

Authors

Tagami T, Miyano E, Sadahiro J, Okuyama M, Iwasaki T, Kimura A

Title

Two Novel Glycoside Hydrolases Responsible for the Catabolism of Cyclobis-(1-->6)-alpha-nigerosyl.

Journal

J Biol Chem 291:16438-47 (2016)
DOI:10.1074/jbc.M116.727305

Sequence

[kfl:Kfla_1896]

Other DBs

ExplorEnz - The Enzyme Database:

3.2.1.205

IUBMB Enzyme Nomenclature:

3.2.1.205

ExPASy - ENZYME nomenclature database:

3.2.1.205

BRENDA, the Enzyme Database:

3.2.1.205

DBGET integrated database retrieval system