KEGG   ENZYME: 3.2.1.63Help
Entry
EC 3.2.1.63                 Enzyme                                 

Name
1,2-alpha-L-fucosidase;
almond emulsin fucosidase;
alpha-(1->2)-L-fucosidase
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
2-alpha-L-fucopyranosyl-beta-D-galactoside fucohydrolase
Reaction(IUBMB)
methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside + H2O = L-fucose + methyl beta-D-galactoside [RN:R04270 R06118]
Reaction(KEGG)
Substrate
methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside [CPD:C04698];
H2O [CPD:C00001]
Product
L-fucose [CPD:C01019];
methyl beta-D-galactoside [CPD:C03619]
Comment
Highly specific for non-reducing terminal L-fucose residues linked to D-galactose residues by a 1,2-alpha-linkage. Not identical with EC 3.2.1.111 1,3-alpha-L-fucosidase.
History
EC 3.2.1.63 created 1972
Reference
1  [PMID:5460888]
  Authors
Bahl OP.
  Title
Glycosidases of aspergillus niger. II. Purification and general properties of 1,2-alpha-L-fucosidase.
  Journal
J. Biol. Chem. 245 (1970) 299-304.
Reference
2  [PMID:18111]
  Authors
Ogata-Arakawa M, Muramatsu T, Kobata A.
  Title
alpha-L-fucosidases from almond emulsin: characterization of the two enzymes with different specificities.
  Journal
Arch. Biochem. Biophys. 181 (1977) 353-8.
Reference
3  [PMID:7458]
  Authors
Reglero A, Cabezas JA.
  Title
Glycosidases of molluscs. Purification and properties of alpha-L-fucosidase from Chamelea gallina L.
  Journal
Eur. J. Biochem. 66 (1976) 379-87.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37288-45-2

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