KEGG   ENZYME: 3.2.2.16Help
Entry
EC 3.2.2.16                 Enzyme                                 

Name
methylthioadenosine nucleosidase;
5'-methylthioadenosine nucleosidase;
MTA nucleosidase;
MeSAdo nucleosidase;
methylthioadenosine methylthioribohydrolase
Class
Hydrolases;
Glycosylases;
Hydrolysing N-glycosyl compounds
BRITE hierarchy
Sysname
S-methyl-5'-thioadenosine adeninehyrolase
Reaction(IUBMB)
S-methyl-5'-thioadenosine + H2O = S-methyl-5-thio-D-ribose + adenine [RN:R01401]
Reaction(KEGG)
Substrate
S-methyl-5'-thioadenosine [CPD:C00170];
H2O [CPD:C00001]
Product
S-methyl-5-thio-D-ribose [CPD:C03089];
adenine [CPD:C00147]
Comment
Does not act on S-adenosylhomocysteine. cf. EC 3.2.2.9 adenosylhomocysteine nucleosidase.
History
EC 3.2.2.16 created 1983, modified 2004
Pathway
ec00270  Cysteine and methionine metabolism
ec01100  Metabolic pathways
Orthology
K01244  5'-methylthioadenosine nucleosidase
Genes
ATH: AT4G34840 AT4G38800(MTN1)
ALY: ARALYDRAFT_490644 ARALYDRAFT_491173
CRB: 17879840 17880545
CSAT: 104716161 104720792 104729184 104729734
EUS: EUTSA_v10025990mg EUTSA_v10026821mg
BRP: 103834385 103834389 103835162
BNA: 106357695 106361013 106361473 106410453 106421765 111213229
BOE: 106301709 106329576 106336199
THJ: 104807783 104819635
CPAP: 110816481
CIT: 102629213
TCC: 18607620
GRA: 105795383
VRA: 106759877
CAM: 101501070
ADU: 107460479
AIP: 107605910
LJA: Lj1g3v3343930.1(Lj1g3v3343930.1)
LANG: 109326550
FVE: 101300865
CSV: 101204791
CMO: 103490311
MCHA: 111008032
RCU: 8285153
JCU: 105643791
VVI: 100233110(GRIP58)
SLY: 101256428
SPEN: 107008065
SOT: 102581476
CANN: 107840524
NSY: 104245452
NTO: 104112984
BVG: 104903996
SOE: 110786505
NNU: 104605304
OSA: 4339898
DOSA: Os06t0112200-01(Os06g0112200)
OBR: 102702761
BDI: 100839737
ATS: 109764083(LOC109764083) 109770233(LOC109770233)
SBI: 8060610
SITA: 101781591
MUS: 103973409
DCT: 110116757
AOF: 109819449
APRO: F751_3141
 » show all
Taxonomy
Reference
1  [PMID:6783408]
  Authors
Guranowski AB, Chiang PK, Cantoni GL.
  Title
5'-Methylthioadenosine nucleosidase. Purification and characterization of the enzyme from Lupinus luteus seeds.
  Journal
Eur. J. Biochem. 114 (1981) 293-9.
Other DBs
ExplorEnz - The Enzyme Database: 3.2.2.16
IUBMB Enzyme Nomenclature: 3.2.2.16
ExPASy - ENZYME nomenclature database: 3.2.2.16
BRENDA, the Enzyme Database: 3.2.2.16
CAS: 50812-28-7

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