KEGG   ENZYME: 3.4.11.14Help
Entry
EC 3.4.11.14                Enzyme                                 

Name
cytosol alanyl aminopeptidase;
arylamidase;
aminopolypeptidase;
thiol-activated aminopeptidase;
human liver aminopeptidase;
puromycin-sensitive aminopeptidase;
soluble alanyl aminopeptidase;
cytosol aminopeptidase III;
alanine aminopeptidase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Aminopeptidases
BRITE hierarchy
Reaction(IUBMB)
Release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides
Comment
A puromycin-sensitive, Co2+-activated zinc-sialoglycoprotein that is generally cytosolic. Multiple forms are widely distributed in mammalian tissues and body fluids. In peptidase family M1 (membrane alanyl aminopeptidase family)
History
EC 3.4.11.14 created 1978
Orthology
K01263  
cytosol alanyl aminopeptidase
Genes
EHI: 
EHI_158320(242.t00016)
TBR: 
Tb927.7.6270(Tb07.2F2.590)
TCR: 
LMA: 
LIF: 
XCC: 
XCC3168(pepN)
XCB: 
XCA: 
XCP: 
XCV: 
XCV3437(pepN3)
XAC: 
XAC3318(pepN)
XCI: 
XCT: 
XAX: 
XACM_3213(pepN3)
XAO: 
XOO: 
XOO3393(pepN)
XOM: 
XOO3194(XOO3194)
XOP: 
XOR: 
PSD: 
FAU: 
RHD: 
ACB: 
ABM: 
ABY: 
ABC: 
ABN: 
ABB: 
SWD: 
SWP: 
SVO: 
PAT: 
PSM: 
GAG: 
KKO: 
CFU: 
ACP: 
MXA: 
MFU: 
LJO: 
LGA: 
 » show all
Taxonomy
Reference
1  [PMID:4841062]
  Authors
Starnes WL, Behal FJ.
  Title
A human liver aminopeptidase. The amino acid and carbohydrate content, and some physical properties of a sialic acid containing glycoprotein.
  Journal
Biochemistry. 13 (1974) 3221-7.
Reference
2  [PMID:698181]
  Authors
Kao YJ, Starnes WL, Behal FJ.
  Title
Human kidney alanine aminopeptidase: physical and kinetic properties of a sialic acid containing glycoprotein.
  Journal
Biochemistry. 17 (1978) 2990-4.
Reference
3  [PMID:6108169]
  Authors
Sidorowicz W, Hsia WC, Maslej-Zownir O, Behal FJ.
  Title
Multiple molecular forms of human alanine aminopeptidase: immunochemical properties.
  Journal
Clin. Chim. Acta. 107 (1980) 245-56.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
243859-94-1

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