KEGG   ENZYME: 3.4.14.2Help
Entry
EC 3.4.14.2                 Enzyme                                 

Name
dipeptidyl-peptidase II;
dipeptidyl aminopeptidase II;
dipeptidyl arylamidase II;
carboxytripeptidase;
dipeptidyl peptidase II;
dipeptidyl arylamidase II;
DAP II;
dipeptidyl(amino)peptidase II;
dipeptidylarylamidase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Dipeptidyl-peptidases and tripeptidyl-peptidases
BRITE hierarchy
Reaction(IUBMB)
Release of an N-terminal dipeptide, Xaa-Yaa!, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides
Comment
A lysosomal serine-type peptidase in family S28 (Pro-X carboxypeptidase family); maximally active at acidic pH
History
EC 3.4.14.2 created 1978
Orthology
K01276  
dipeptidyl-peptidase II
Genes
HSA: 
29952(DPP7)
PTR: 
473101(DPP7)
PPS: 
100976342(DPP7)
GGO: 
101136044(DPP7)
PON: 
100174214(DPP7)
NLE: 
100595263(DPP7)
MCC: 
721595(DPP7)
MCF: 
101867244(DPP7)
RRO: 
104669635(DPP7)
CJC: 
100413498(DPP7)
MMU: 
83768(Dpp7)
RNO: 
83799(Dpp7)
CGE: 
100756223(Dpp7)
NGI: 
103741174(Dpp7)
HGL: 
101724543(Dpp7)
TUP: 
102470111(DPP7)
CFA: 
607003(DPP7)
AML: 
100467965(DPP7)
UMR: 
103675309(DPP7)
FCA: 
101095966(DPP7)
PTG: 
102948665(DPP7)
BTA: 
100125760(DPP7)
BOM: 
102277526(DPP7)
PHD: 
102323507(DPP7)
CHX: 
102182320(DPP7)
SSC: 
100626630(DPP7)
CFR: 
102514636(DPP7)
BACU: 
103002313(DPP7)
LVE: 
103077546(DPP7)
ECB: 
100059924(DPP7)
MYD: 
102751478(DPP7)
PALE: 
102890830(DPP7)
MDO: 
100022760(DPP7)
SHR: 
100918941(DPP7)
GGA: 
417297(DPP7)
MGP: 
100543847(DPP7)
CJO: 
107321630(DPP7)
APLA: 
101791397(DPP7)
TGU: 
100226334(DPP7)
GFR: 
102031390(DPP7)
FAB: 
101815871(DPP7)
CCW: 
104688194(DPP7)
FPG: 
101914257(DPP7)
FCH: 
102051827(DPP7)
CLV: 
102083967(DPP7)
AAM: 
106494235(DPP7)
ASN: 
102372722(DPP7)
AMJ: 
102571172(DPP7)
PSS: 
CMY: 
102944633(DPP7)
ACS: 
100562590(dpp7)
PBI: 
103050059(DPP7)
GJA: 
107123276(DPP7)
DRE: 
503737(dpp7)
TRU: 
101061692(dpp7)
MZE: 
101469493(dpp7)
OLA: 
101156583(dpp7)
XMA: 
102233162(dpp7)
LCM: 
102363610(DPP7)
CMK: 
103180401(dpp7)
BFO: 
CIN: 
SPU: 
SKO: 
LGI: 
CRG: 
OBI: 
SMM: 
NVE: 
HMG: 
TAD: 
MPP: 
TRE: 
ACAN: 
AAF: 
 » show all
Taxonomy
Reference
1  [PMID:4969969]
  Authors
McDonald JK, Leibach FH, Grindeland RE, Ellis S.
  Title
Purification of  dipeptidyl aminopeptidase II (dipeptidyl arylamidase II) of the anterior pituitary gland. Peptidase and dipeptide esterase activities.
  Journal
J. Biol. Chem. 243 (1968) 4143-50.
Reference
2
  Authors
McDonald, J.K. and Schwabe, C.
  Title
Intracellular exopeptidases.
  Journal
In: Barrett, A.J. (Ed.), Proteinases in Mammalian Cells and Tissues, North-Holland Publishing Co., Amsterdam, 1977, p. 311-391.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
76199-23-0

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