KEGG   ENZYME: 3.4.16.6Help
Entry
EC 3.4.16.6                 Enzyme                                 

Name
carboxypeptidase D;
cereal serine carboxypeptidase II;
Saccharomyces cerevisiae KEX1 gene product;
carboxypeptidase Kex1;
gene KEX1 serine carboxypeptidase;
KEX1 carboxypeptidase;
KEX1 proteinase;
KEX1DELTAp;
CPDW-II;
serine carboxypeptidase (misleading);
Phaseolus proteinase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine-type carboxypeptidases
BRITE hierarchy
Reaction(IUBMB)
Preferential release of a C-terminal arginine or lysine residue
Comment
A carboxypeptidase with optimum pH 4.5-6.0, inhibited by diisopropyl fluorophosphate, and sensitive to thiol-blocking reagents (reviewed in [1]). In peptidase family S10 (carboxypeptidase C family).
History
EC 3.4.16.6 created 1972 as EC 3.4.12.1, transferred 1978 to EC 3.4.16.1, part transferred 1993 to EC 3.4.16.6 (EC 3.4.16.3 created 1972 as EC 3.4.12.12, transferred 1978 to EC 3.4.16.3, transferred 1992 to EC 3.4.16.1), (EC 3.4.21.13 created 1972, transferred 1978 to EC 3.4.16.1), modified 2011
Orthology
K01288  
carboxypeptidase D
Genes
ZMA: 
SCE: 
YGL203C(KEX1)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0E00660(NCAS0E00660)
NDI: 
NDAI_0I02850(NDAI0I02850)
TPF: 
TPHA_0A05770(TPHA0A05770)
TBL: 
TBLA_0I03220(TBLA0I03220)
TDL: 
TDEL_0D05800(TDEL0D05800)
KAF: 
KAFR_0D01410(KAFR0D01410)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CaO19.7020(KEX1) CaO19_7020(CaJ7_0112)
CTP: 
COT: 
CDU: 
CTEN: 
YLI: 
CLU: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_2862174(AO090005001632) AOR_1_894024(AO090010000534)
ANG: 
ANI_1_1212124(An14g02150) ANI_1_1592074(An08g00430) ANI_1_658034(An03g05200) ANI_1_998064(An07g08030)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
DSQ: 
PCO: 
SHS: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MPR: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT37296(AGABI1DRAFT_37296) AGABI1DRAFT45474(AGABI1DRAFT_45474) AGABI1DRAFT70057(AGABI1DRAFT_70057) AGABI1DRAFT84490(AGABI1DRAFT_84490)
ABV: 
AGABI2DRAFT195700(AGABI2DRAFT_195700) AGABI2DRAFT205752(AGABI2DRAFT_205752) AGABI2DRAFT68978(AGABI2DRAFT_68978) AGABI2DRAFT79914(AGABI2DRAFT_79914)
CPUT: 
SLA: 
UMA: 
PFP: 
MGL: 
PGR: 
MLR: 
WSE: 
DDI: 
DFA: 
PTI: 
TPS: 
PIF: 
NGR: 
 » show all
Taxonomy
Reference
1
  Authors
Breddam, K.
  Title
Serine carboxypeptidases. A review.
  Journal
Carlsberg Res. Commun. 51 (1986) 83-128.
Reference
2
  Authors
Breddam, K., Sorensen, S.B. and Svendsen, I.
  Title
Primary structure and enzymatic properties of carboxypeptidase II from wheat bran.
  Journal
Carlsberg Res. Commun. 52 (1987) 297-311.
Reference
3  [PMID:3301004]
  Authors
Dmochowska A, Dignard D, Henning D, Thomas DY, Bussey H.
  Title
Yeast KEX1 gene encodes a putative protease with a carboxypeptidase B-like function involved in killer toxin and alpha-factor precursor processing.
  Journal
Cell. 50 (1987) 573-84.
  Sequence
[sce:YGL203C]
Reference
4  [PMID:1390755]
  Authors
Liao DI, Breddam K, Sweet RM, Bullock T, Remington SJ.
  Title
Refined atomic model of wheat serine carboxypeptidase II at 2.2-A resolution.
  Journal
Biochemistry. 31 (1992) 9796-812.
  Sequence
[up:P08819]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
153967-26-1

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