KEGG   ENZYME: 3.4.21.49Help
Entry
EC 3.4.21.49                Enzyme                                 

Name
hypodermin C;
Hypoderma collagenase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Hydrolysis of proteins including native collagen at !Ala bond leaving an N-terminal (75%) and a C-terminal (25%) fragment
Comment
From the larva of a warble fly, Hypoderma lineatum. Little action on small molecule substrates of trypsin, chymotrypsin, elastase or microbial collagenases. In peptidase family S1 (trypsin family)
History
EC 3.4.21.49 created 1981
Reference
1  [PMID:230030]
  Authors
Lecroisey A, Boulard C, Keil B.
  Title
Chemical and enzymatic characterization of the collagenase from the insect Hypoderma lineatum.
  Journal
Eur. J. Biochem. 101 (1979) 385-93.
  Sequence
Reference
2  [PMID:2995028]
  Authors
Lecroisey A, Keil B.
  Title
Specificity of the collagenase from the insect Hypoderma lineatum.
  Journal
Eur. J. Biochem. 152 (1985) 123-30.
  Sequence
Reference
3  [PMID:3034899]
  Authors
Lecroisey A, Gilles AM, De Wolf A, Keil B.
  Title
Complete amino acid sequence of the collagenase from the insect Hypoderma lineatum.
  Journal
J. Biol. Chem. 262 (1987) 7546-51.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
122191-36-0

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