KEGG   ENZYME: 3.4.21.55Help
Entry
EC 3.4.21.55                Enzyme                                 

Name
venombin AB;
gabonase;
okinaxobin II;
Bitis gabonica venom serine proteinase;
afaacytin
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Selective cleavage at Arg! bonds in fibrinogen to form fibrin and release fibrinopeptides A and B
Comment
From the venom of the Gaboon viper Bitis gabonica. Activates Factor XIII. Not inhibited by antithrombin III/heparin or hirudin, unlike EC 3.4.21.5, thrombin
History
EC 3.4.21.55 created 1989
Reference
1  [PMID:3522580]
  Authors
Pirkle H, Theodor I, Miyada D, Simmons G.
  Title
Thrombin-like enzyme from the venom of Bitis gabonica. Purification, properties, and coagulant actions.
  Journal
J. Biol. Chem. 261 (1986) 8830-5.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
104003-74-9

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