KEGG   ENZYME: 3.4.21.65Help
Entry
EC 3.4.21.65                Enzyme                                 

Name
thermomycolin;
thermomycolase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Rather nonspecific hydrolysis of proteins. Preferential cleavage: Ala!, Tyr!, Phe! in small molecule substrates
Comment
A peptidase of family S8 (subtilisin family) from the thermophilic fungus Malbranchea pulchella var. sulfurea containing Cys, but not inhibited by p-mercuribenzoate. Very thermostable. Formerly included in EC 3.4.21.14
History
EC 3.4.21.65 created 1992 (EC 3.4.21.14 created 1961 as EC 3.4.4.16, transferred 1972 to EC 3.4.21.14, modified 1986, part incorporated 1992)
Reference
1  [PMID:1012007]
  Authors
Gaucher GM, Stevenson KJ.
  Title
Thermomycolin.
  Journal
Methods. Enzymol. 45 (1976) 415-33.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
52233-31-5

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