KEGG   ENZYME: 3.4.21.9Help
Entry
EC 3.4.21.9                 Enzyme                                 

Name
enteropeptidase;
enterokinase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Activation of trypsinogen by selective cleavage of Lys6!Ile bond
Comment
Is not inhibited by protein inhibitors of trypsin. In peptidase family S1 (trypsin family).
History
EC 3.4.21.9 created 1961 as EC 3.4.4.8, transferred 1972 to EC 3.4.21.9
Orthology
K01316  
protease, serine, 7 (enterokinase)
Genes
HSA: 
5651(TMPRSS15)
PTR: 
458478(TMPRSS15)
PPS: 
100992890(TMPRSS15)
GGO: 
101151821(TMPRSS15)
MCC: 
100423099(TMPRSS15)
MCF: 
102135270(TMPRSS15)
MMU: 
19146(Tmprss15)
RNO: 
288291(Tmprss15)
CGE: 
100754500(Tmprss15)
HGL: 
101719326(Tmprss15)
TUP: 
102474054(TMPRSS15)
CFA: 
487700(TMPRSS15)
AML: 
FCA: 
101088868(TMPRSS15)
BTA: 
282009(TMPRSS15)
BOM: 
102265063(TMPRSS15)
PHD: 
102338924(TMPRSS15)
CHX: 
102180152(TMPRSS15)
SSC: 
397152(TMPRSS15)
CFR: 
102520122(TMPRSS15)
ECB: 
100067591(TMPRSS15)
MYB: 
102249267(TMPRSS15)
MDO: 
SHR: 
100928791(TMPRSS15)
OAA: 
GGA: 
427967(TMPRSS15)
MGP: 
TGU: 
100220466(TMPRSS15)
FAB: 
101817773(TMPRSS15)
PHI: 
102106374(TMPRSS15)
APLA: 
101801915(TMPRSS15)
FPG: 
101922858(TMPRSS15)
FCH: 
102047221(TMPRSS15)
CLV: 
102094803(TMPRSS15)
ASN: 
102380816(TMPRSS15)
PSS: 
102446226(TMPRSS15)
ACS: 
100554809(tmprss15)
XTR: 
100490249(tmprss15)
DRE: 
100148042(tmprss15)
TRU: 
MZE: 
OLA: 
100125449(ep-1) 100125450(ep-2)
XMA: 
LCM: 
BFO: 
 » show all
Taxonomy
Reference
1  [PMID:2658218]
  Authors
Light A, Janska H.
  Title
Enterokinase (enteropeptidase): comparative aspects.
  Journal
Trends. Biochem. Sci. 14 (1989) 110-2.
  Organism
Homo sapiens [GN:hsa], Bos taurus [GN:bta], Sus scofa [GN:ssc]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9014-74-8

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